Pregabalin is an antiepileptic medication. It has antiseizure (fits reducing) as well as antinociceptive (pain relieving) properties. The detailed mechanism of action is not fully understood. However, it is believed that it works by binding with calcium channels in the brain and nerve cells to reduce the activity of neurotransmitters (chemical messengers). Thus, it regulates the activity of the brain and nerves to treat seizures (fits) and pain.
Pregalex belongs to anticonvulsants class of medicines. It is used to treat seizures. It is also helpful in treating nerve pain (neuropathic pain) which could be due to diabetes, shingles, or injury. It is also used in fibromyalgia (a long-lasting condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling asleep or staying asleep). In some cases, your doctor may prescribe this medicine for the treatment of anxiety.
Q. Pregalex has varied roles, does it work in the same way for each disease?
No, Pregalex works in different ways for different diseases. In epilepsy, it stops seizures by reducing the abnormal electrical activity in the brain. In chronic pain, it blocks pain messages travelling from brain to spine.
Q. I have been prescribed Pregalex for pain due to shingles. When can I expect relief from pain?
Pregalex may require a few weeks to see full benefits. However, people have felt relief from pain after a week of starting Pregalex.
Q. How long do I need to take Pregalex?
Duration for the use of Pregalex depends on the condition for which you are taking this medicine. If you are taking it for epilepsy, which if controlled by Pregalex, you may have to continue it for years. If you are taking it for pain (neuropathic and fibromyalgia pain), it is likely that once your symptoms have gone you will have to continue taking it for several months to ensure stopping the problem from coming back. It is advised to not stop before consulting your doctor.
Q. Is it necessary to continue taking Pregalex even if I feel fine?
Even if you feel fine, you should not stop Pregalex. If you are taking it for epilepsy and suddenly stop its consumption, you may have seizures that will not stop. Stopping it suddenly may result in withdrawal symptoms and you may experience anxiety, difficulty in sleeping, feeling sick, pain, and sweating. These can be prevented if dose of Pregalex is reduced gradually.
Q. Is Pregalex addictive?
Addiction to Pregalex is more common in people who take it for unauthorized reasons. Taking more than the recommended doses and for long periods of time may also cause addiction. In addition to that, any person who has a history of drug abuse should never use Pregalex. In case you feel you are becoming physically dependent on Pregalex, inform your doctor immediately.
Q. Can I take diazepam and Pregalex together?
Yes, Pregalex and diazepam can be used together but there might be a chance of increased side effects, since both act on the brain to depress excessive activity.
Q. Can Pregalex and gabapentin be taken together for fibromyalgia?
Yes, they can be used together but chances of side effects may be higher with their combined use.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 3rd Dec 2019. The medicine details are for information purpose only. Consult a doctor before taking any medicine.