Glimepiride + Metformin + Pioglitazone is a combination of three antidiabetic medicines: Glimepiride + Metformin + Pioglitazone1, Glimepiride + Metformin + Pioglitazone2 and Glimepiride + Metformin + Pioglitazone3. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride + Metformin + Pioglitazone1 is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Glimepiride + Metformin + Pioglitazone2 is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Glimepiride + Metformin + Pioglitazone3 is a thiazolidinedione which further increases insulin sensitivity.
No, it is not safe to drink alcohol while using Geniride MP. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.
Q. What should I inform the doctor before taking Geniride MP?
Before taking Geniride MP inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.
Q. Can the use of Geniride MP lead to Vitamin B12 deficiency?
Yes, the use of Geniride MP can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.
Q. Can the use of Geniride MP cause hypoglycemia?
Yes, the use of Geniride MP can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry some sugary item like a candy or chocolate with you.
Q. What are the instructions for the storage and disposal of Geniride MP?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 31st May 2019. The medicine details are for information purpose only. Consult a doctor before taking any medicine.