Q. What are the recommended storage conditions for Apriglim-MF 1 Tablet SR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
Q. Can the use of Apriglim-MF 1 Tablet SR lead to lactic acidosis?
Yes, the use of Apriglim-MF 1 Tablet SR can lead to lactic acidosis. It is a medical emergency that is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful to patients with underlying kidney disease, old age patients, or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or slow heart rate. If you have these symptoms, stop taking Apriglim-MF 1 Tablet SR and consult your doctor immediately.
Q. What is Apriglim-MF 1 Tablet SR?
Apriglim-MF 1 Tablet SR is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
Q. What are the possible side effects of Apriglim-MF 1 Tablet SR?
The use of Apriglim-MF 1 Tablet SR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. In long-term use, it can also lead to Vitamin B12 deficiency.
Q. Can the use of Apriglim-MF 1 Tablet SR lead to Vitamin B12 deficiency?
Yes, the use of Apriglim-MF 1 Tablet SR can cause Vitamin B12 deficiency with long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status, and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.
Q. Can the use of Apriglim-MF 1 Tablet SR cause hypoglycemia?
Yes, the use of Apriglim-MF 1 Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey, or fruit juice with you.
Q. Is it safe to take alcohol while I am also taking Apriglim-MF 1 Tablet SR?
No, it is not safe to take Apriglim-MF 1 Tablet SR along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.