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NMO with MOG Antibody Profile

NMO with MOG Antibody Profile near me in Cuttack

Also referred as
Neuromyelitis Optica Antibody
Myelin Oligodendrocyte Glycoprotein Antibody
Aquaporin 4
For men & women
Earliest reports in
144-168 hours
Contains
2 tests
Know more about this test

The NMO with MOG Antibody Profile is a group of blood tests that help detect two types of autoimmune conditions: neuromyelitis optica (NMO) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD). These conditions affect the brain, spinal cord, and nerves of the eyes. This test checks for two specific antibodies in the blood: aquaporin-4 (AQP4) IgG antibodies and MOG (myelin oligodendrocyte glycoprotein) IgG antibodies. Finding these antibodies helps doctors to confirm the diagnosis and guide targeted treatment. It is widely available in Cuttack with Tata 1mg labs at an affordable price. 

Individuals with one or more of the following symptoms may benefit from taking the NMO with MOG Antibody Profile: weakness in the back and arms, tight or painful muscle spasms in the arms or legs, and discomfort or unusual sensations in the limbs. Some may also experience increased sensitivity to heat or cold, along with issues related to bladder control, bowel movements, or sexual dyfunction. These symptoms may indicate inflammation or damage in the brain, spinal cord, or optic nerves.

This test plays a crucial role in early diagnosis of NMOSD and MOG, especially when imaging results are inconclusive, and can prevent irreversible damage to the CNS through timely treatment.

No special preparation is required for the NMO with MOG Antibody Profile. Inform the doctor about all the medications (e.g., immunosuppressants, steroids, etc.) and supplements currently being taken, as some of them may affect the test results, potentially requiring dosage adjustments or temporary discontinuation before the test.

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Understanding NMO with MOG Antibody Profile

Neuromyelitis optica (NMO) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are autoimmune conditions that affect the central nervous system (CNS). These diseases occur when the body’s immune system attacks its own nervous system, especially the optic nerves, spinal cord, and brain. This can lead to vision loss, muscle weakness, numbness, pain, and bladder or bowel problems.

The NMO with MOG Antibody Profile checks for the presence of two specific antibodies in the blood: aquaporin-4 (AQP4) IgG antibodies, which are strongly linked to NMOSD (a severe form of NMO or Neuromyelitis Optica Spectrum Disorder), and myelin oligodendrocyte glycoprotein (MOG) IgG antibodies, which indicate MOGAD. The detection of these antibodies helps the doctor confirm the diagnosis, especially when the symptoms of these conditions overlap with other central nervous system disorders like multiple sclerosis (MS). Accurate diagnosis is important because the treatment and disease progression differ across these conditions.

Individuals with one or more of the following symptoms may benefit from taking the NMO with MOG Antibody Profile: weakness or numbness in the arms or legs, tight or painful muscle spasms in the arms or legs, and discomfort or unusual sensations in the limbs. Some may also experience issues related to bladder control, bowel movements, or sexual dysfunction. These symptoms may indicate inflammation or damage in the brain, spinal cord, or optic nerves.

This test helps in early diagnosis of NMOSD and MOGAD, especially when imaging results are inconclusive, which, with timely treatment, can help prevent irreversible damage to the Central nervous system (CNS).

No special preparation is required for the NMO with MOG Antibody Profile. Inform the doctor about all the medications (e.g., immunosuppressants, steroids, etc.) and supplements currently being taken, as some of them may affect the test results, so your doctor may adjust the dose or ask you to pause them before the test.

Test result ranges are approximate and may differ slightly between labs, depending on the methodology and laboratory guidelines. Do not self-medicate, and always consult a doctor to understand the test results correctly.

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does NMO with MOG Antibody Profile measure?

Contains 2 tests

The NMO with MOG Antibody Profile is a group of blood tests that checks for two specific antibodies linked to nerve-related conditions:

1. Aquaporin-4 (AQP4) IgG antibodies – These antibodies attack water channels in the brain and spinal cord, especially the optic nerve. Their presence helps diagnose a condition called neuromyelitis optica spectrum disorder (NMOSD).

2. Myelin oligodendrocyte glycoprotein (MOG) IgG antibodies – These antibodies damage the protective covering (myelin) around nerves. They are linked to MOG antibody disease (MOGAD), which is different from both NMOSD and multiple sclerosis (MS).

A high positive result strongly supports the diagnosis of MOG-antibody-associated disease, but results should always be interpreted along with your symptoms and MRI findings. Similar principles apply to aquaporin-4 (AQP4) antibodies. A negative result does not rule out NMOSD or other demyelinating diseases.

NMO (NEUROMYELITIS OPTICA)
MOG (MYELIN OLIGODENDROCYTE GLYCOPROTEIN)

FAQs related to NMO with MOG Antibody Profile in Cuttack

The NMO with MOG Antibody Profile is a group of blood tests that check for the presence of aquaporin-4 IgG and MOG IgG antibodies to diagnose NMOSD or MOGAD, which are autoimmune disorders affecting the central nervous system.
The NMO with MOG Antibody Profile is done to distinguish NMO from multiple sclerosis (MS) and other similar conditions. These antibodies are very specific for NMO and rarely seen in MS or healthy people.
The NMO with MOG Antibody Profile is usually done when a doctor suspects conditions like neuromyelitis optica spectrum disorder (NMOSD) or MOG antibody disease (MOGAD). It is recommended if you have symptoms such as sudden vision loss, eye pain, weakness in the arms or legs, numbness, or problems with bladder or bowel control. These symptoms may point to inflammation in the optic nerves or the spinal cord. The test helps doctors confirm the diagnosis and plan the right treatment.
Individuals experiencing certain neurological symptoms may benefit from taking this test. These symptoms include weakness or numbness in the arms or legs, painful and tight muscle spasms in the arms or legs, and general discomfort in the limbs. Some individuals may also notice increased sensitivity to heat or cold, along with problems related to bladder control, bowel movements, or sexual dysfunction. These signs could point to underlying nerve inflammation, and the test can help in identifying the cause.
MRI shows structural changes in the brain or spine, but may not be able to distinguish between MS, NMOSD, or MOGAD. This blood test shows whether you have certain antibodies, which helps point to a specific condition.
Yes. In Cuttack, you can schedule the NMO with MOG Antibody Profile near you with Tata 1mg Labs. The profile is easy to book, cost-effective, and available with a comprehensive report.
Yes, home sample collection for the NMO with MOG Antibody Profile is readily available in Cuttack. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule the NMO with MOG Antibody Profile with Tata 1mg Labs in Cuttack, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want to the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Cuttack. The NMO with MOG Antibody Profile is available at an affordable price of Rs. 6499.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 144-168 hours to provide the reports of the NMO with MOG Antibody Profile in Cuttack.
Content created by
Written by:
Dr. Lipika Khurana
PGDHHM, BDS
Reviewed by:
Dr. Swati Gupta (Anand)
MD Lab Medicine, MBBS
Want to know moreRead our editorial policy
Last Updated21st Dec 2025

NMO with MOG Antibody Profile test price for other cities

Price inBangaloreRs. 7229
Price inNew DelhiRs. 6299
Price inKolkataRs. 6899
Price inHyderabadRs. 7410
Price inGurgaonRs. 6299

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Contains 2 tests
NMO (NEUROMYELITIS OPTICA)
MOG (MYELIN OLIGODENDROCYTE GLYCOPROTEIN)