Lactate Dehyderogenase, Serum
Understanding Lactate Dehyderogenase, Serum
What is Lactate Dehyderogenase, Serum?
The Serum Lactate Dehydrogenase (LDH) test measures the levels of the enzyme lactate dehydrogenase in the blood. This enzyme is majorly involved in energy production and is found in nearly all of the body’s cells, with the highest levels in the cells of the heart, liver, muscles and kidneys. It is released in the bloodstream as a result of damage to the tissues following an injury.
The serum LDH test is a nonspecific test that can predict cellular injury due to tissue destruction or disease, but it does not give clues about the location of the damage. Higher than normal LDH levels can be seen in heart attack, kidney disease, and muscle injury.
What is Lactate Dehyderogenase, Serum used for?
The Serum Lactate Dehydrogenase Test is performed:
· To determine the presence and extent of tissue damage
· To detect progressive diseases like anemia, severe infections, etc.
· To monitor disease progress and treatment efficacy for liver and kidney diseases
· To help determine the stage and progress of certain cancers like lymphoma, leukemia, etc., and monitor treatment efficacy
Interpreting Lactate Dehyderogenase, Serum results
Normal range (Approx.):
· Newborns: 160 to 450 units/L
· Infants: 100 to 250 units/L
· Child: 60 to 170 units/L
· Adult/elderly adult: 100 to 190 units/L
Higher than normal levels of lactate dehydrogenase indicates the presence of conditions causing damage to the body tissues. Further tests are performed to determine the exact location and extent of the condition.