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HLA B27 (Human Leukocyte Antigen B27) - PCR

HLA B27 (Human Leukocyte Antigen B27) - PCR near me in Ranchi

Also referred as
Human leukocyte A antigen
Histocompatibility leukocyte A antigen
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An HLA B27 (Human Leukocyte Antigen B27) - PCR test is a blood test that helps to identify the presence of Human Leukocyte Antigen B27(HLA B-27), a specific type of protein that is present on the surface of white blood cells (WBCs) that helps the body's immune system tell the difference between its own cells and foreign/harmful substances. This test is widely available with Tata 1mg labs at an affordable price in Ranchi

Your doctor may suggest an HLA B-27 test if you experience signs and symptoms such as stiffness and chronic pain in the back, neck, or chest, inflammation in eyes, urethra, and joints, the appearance of skin lesions, recurring fever, abdominal pain, or digestive problems indicative of an autoimmune disorder. Additionally, this test is also used during an organ transplant to match donated tissue with a transplant recipient  to minimize the risk of organ rejection and improve the success of the transplantation procedure. No special preparation is needed for this test. You may eat and drink as per your daily routine.

 

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Understanding HLA B27 (Human Leukocyte Antigen B27) - PCR

Human Leukocyte Antigens (HLAs) genes play a crucial role in the immune system, and the HLA B27 variant is associated with certain autoimmune conditions, especially a group of joint-related conditions known as seronegative spondyloarthropathies. These include ankylosing spondylitis, reactive arthritis, psoriatic arthritis, and juvenile idiopathic arthritis.

This test uses a method called PCR (polymerase chain reaction), which is more accurate and sensitive than other methods like flow cytometry. It helps doctors detect the HLA-B27 gene, assess the risk, and monitor the condition if symptoms are already present.

The doctor may suggest an HLA B27 (Human Leukocyte Antigen B27) - PCR test if there are signs and symptoms such as chronic back pain, joint pain, stiffness, or inflammation in the eyes, urethra, and joints, or have a family history of autoimmune conditions. The HLA B27 test is also used to match donated tissue to the tissue of the organ transplant recipient.

Usually, no special preparation is needed for this test. Eat and drink as per the daily routine. Also, inform the doctor about any medications being taken, as some medications may influence the test results if taken before this test.

Test result ranges may vary slightly across laboratories. Talk to your doctor to understand what the result means. Based on the findings, they may recommend lifestyle changes or medications to manage your health.

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What does HLA B27 (Human Leukocyte Antigen B27) - PCR measure?

An HLA B27 (Human Leukocyte Antigen B27) - PCR test is used to determine the presence or absence of the HLA B27 antigen to rule out the possibility of an autoimmune disorder. This gene is found on the surface of certain white blood cells and may increase the risk of developing conditions like ankylosing spondylitis, reactive arthritis, and psoriatic arthritis.

A positive result means the gene is present, and there may be a higher risk of these conditions. A negative result means the gene is not found. However, it is important to know that not having the HLA B27 gene does not fully rule out autoimmune disorders, as some people without the gene can still develop them.

FAQs related to HLA B27 (Human Leukocyte Antigen B27) - PCR in Ranchi

An HLA B27 (Human Leukocyte Antigen B27) - PCR test is done if you have symptoms like pain and inflammation associated with spine, neck, and chest stiffness. This test helps determine whether you have human leukocyte antigen B27 (HLA B27) on the surface of your cells, and this, in turn, helps assess the possibility that you may be suffering from an autoimmune disorder.
A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
An HLA B27 test is a safe procedure. However, there are some common risks involved when having blood drawn from the arm, such as mild pain, bruising, or bleeding at the injection site. Most of these symptoms go away in a day or two. Serious complications are rare.
Yes. In Ranchi, you can schedule an HLA B27 test near you with Tata 1mg Labs. The test is easy to book, cost-effective, and available with a comprehensive report.
Yes, home sample collection for an HLA B27 test is readily available in Ranchi. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule an HLA B27 test with Tata 1mg Labs in Ranchi, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want in the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Ranchi. An HLA B27 test is available at an affordable price of Rs. 2869.
The e-report of your HLA B27 test can be found on the Tata 1mg app in downloadable PDF form. This allows you to access your test results at convenience and securely share them with your healthcare provider for further consultation and guidance regarding your overall health. You can also opt for a hard copy of the reports at a minimal price.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 120 hours to provide the reports of an HLA B27 test in Ranchi.
Content created by
Written by:
Dr. Lipika Khurana
BDS, PGDHHM
Reviewed by:
Dr. Swati Gupta (Anand)
MD Lab Medicine, MBBS
Want to know moreRead our editorial policy
Last Updated5th Oct 2025

HLA B27 (Human Leukocyte Antigen B27) - PCR test price for other cities

Price inNew DelhiRs. 2879
Price inBangaloreRs. 2569
Price inKolkataRs. 2880
Price inMumbaiRs. 2209
Price inGurgaonRs. 2879

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HLA B27 (Human Leukocyte Antigen B27) - PCR