HIV Genotyping and Drug Resistance Test (RT, PR and INT Genes) near me in Bangalore

HIV is an RNA virus and is the causative agent of acquired immunodeficiency syndrome (AIDS). A combination of drugs known as Antiretroviral therapy (ART) is used for the treatment of AIDS. Drug resistance is reported for all the drugs which are used in clinical use. Drug resistance testing is used to determine whether a patient with HIV-1 has a mutated form of the virus that does not respond to ART. HIV Genotyping and Drug Resistance Test (RT, PR and INT Genes) is used before initiating therapy or when rising viral loads suggest therapy failure in patients undergoing HIV ART therapy. Detection of drug resistance mutations helps to make appropriate changes in ART. Identification of the genotype is important since there is emerging evidence of subtype differences in drug resistance. This is a targeted next-generation sequencing-based CE-IVD test to subtype the HIV-1 strains and identify mutations associated with antiviral drug resistance in Reverse transcriptase (RT), Protease (PR), and Integrase (INT) genes and predict antiviral drug susceptibility to nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), Protease inhibitors and Integrase inhibitors.