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Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Hemoglobin Free, Urine

Also known as Urine Free Hemoglobin
189
You need to provide
Urine
This test is for
Male, Female
Test Preparation
  1. The urine sample must preferably be the midstream urine (part of urine that comes after the first and before the last stream). Collect the urine sample in a sealed and sterile container provided by our sample collection professional. Make sure that the container doesn't come in contact with your skin. Women are advised not to give the sample during the menstrual period unless prescribed.

Understanding Hemoglobin Free, Urine


What is Hemoglobin Free, Urine?

The Hemoglobin Free, Urine is a simple, noninvasive test that detects the presence of free hemoglobin in a urine sample. This test can help identify conditions like hemolysis or blood disorders that might cause RBC breakdown within the bloodstream , thereby releasing the hemoglobin in plasma which gets excreted in urine as hemoglobinuria(presence of hemoglobin in the urine).

Hemoglobin is an iron-containing protein in our RBCs that carries oxygen throughout your body. However, when red blood cells are destroyed (hemolysis), free hemoglobin can be released into the blood and subsequently may pass into the urine. This free hemoglobin can be detected through the Hemoglobin Free, Urine test. Unlike hematuria (blood in urine), where whole red blood cells are present in the urine, free hemoglobin in the urine (hemoglobinuria) is a sign of red blood cell blood disorder. It can be caused by hemolytic anemia, reactions to transfusions, infections, or trauma. It can also suggest severe kidney injury, especially when heme is not adequately filtered by the kidneys. 

The doctor may suggest the Hemoglobin Free, Urine if symptoms of hemolytic anemia are present such as weakness, shortness of breath, palpitations, rapid heartbeat, paler skin, jaundice, or blood in urine. This test may also be advised to an individual having a history of blood transfusions or having infections or kidney disease. It is taken for follow-up treatment responses for blood-related and kidney diseases.

A positive test result shows the presence of hemoglobin in the urine, which may point to an underlying problem. An absence of hemoglobin in urine signifies a negative result, indicating that there is no sign of concern. In cases of hemoglobinuria, doctors may conduct additional tests like blood tests, urine culture, or imaging tests to evaluate the source of hemolysis and help guide proper treatment.

Drink enough water to provide a urine sample. A midstream urine sample should be collected into a sterile container provided by the sample collection professional. Women are advised not to give a urine sample during the menstrual period unless prescribed. Several factors such as vigorous physical activity or menstrual blood, may lead to false-positive test results. Therefore, it is essential to inform the doctor about any recent exercise, medical conditions, or medications that could affect the test results. 

Don't self-medicate at home solely based on these results. Always consult a doctor for a proper understanding of the test results. Narrate the complete medical history to help the doctor correlate the clinical and laboratory findings. The results will help them determine the medical condition and formulate a treatment plan.

What is Hemoglobin Free, Urine used for?

The Hemoglobin Free, Urine test is done: 

  • To evaluate the presence of free hemoglobin in the urine as an indicator of hemolysis or other blood-related disorders.
  • To assess kidney function and detect possible kidney damage associated with hemoglobinuria.
  • To diagnose and monitor hemolytic anemia or blood transfusion reactions.
  • To find the root cause of unexplained symptoms, including dark-colored urine, fatigue, anemia, shortness of breath, blood clots, etc.
  • To detect potential kidney complications from hemoglobin-related conditions.
  • To help diagnose conditions such as sickle cell disease or thalassemia, in which red blood cells break down into fragments or abnormal shapes. 
  • To monitor the cases of hemolytic anemia or kidney disorders causing hemoglobinuria and assess the treatment response.

What does Hemoglobin Free, Urine measure?

The Hemoglobin Free, Urine test is used to detect the presence of free hemoglobin in urine samples. Typically, hemoglobin remains contained within red blood cells and is absent from urine. However, during the process of red blood cell destruction (hemolysis), hemoglobin is released into the blood. When the level of hemoglobin in the blood is too high for the kidneys to filter and reabsorb, it leaks into the urine resulting in hemoglobinuria.

This test plays a crucial role in identifying various underlying health conditions. It can reveal disorders that result in excessive red blood cell destruction, including hemolytic anemia, transfusion reactions, or autoimmune diseases. Additionally, the test aids in evaluating kidney function because elevated levels of free hemoglobin in the urine may result in kidney injury. Furthermore, it serves as a useful screening test for blood disorders such as sickle cell disease or thalassemia, which are characterized by abnormal breakdown of red blood cells.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Hemoglobin Free, Urine


Frequently Asked Questions about Hemoglobin Free, Urine

Q. What is the Hemoglobin Free, Urine test?

The Hemoglobin Free, Urine test detects the presence of free hemoglobin (hemoglobin outside the RBCs) in the urine sample. This can lead to hemoglobinuria, which occurs when red blood cells break down and release hemoglobin into the blood, which is then filtered by the kidneys and excreted in the urine.

Q. When is the Hemoglobin Free, Urine test performed?

This test is performed when an individual has symptoms like reddish/ brownish urine, painful urination, blood in urine, back and abdominal pain, fatigue, jaundice (yellowing of the skin), etc., which may indicate conditions like hemolytic anemia or kidney dysfunction.

Q. How is the Hemoglobin Free, Urine test done?

For this test, a midstream urine sample is typically collected in a sterile container. The sample will then be tested for the presence of hemoglobin.

Q. Is there any preparation needed for the Hemoglobin Free, Urine test?

No specific preparation is required for this test, yet it is important to let your doctor know if you are taking any medication or supplements that can interfere with the results. Additionally, avoid strenuous exercise before the test, as it can give false positive test results.

Q. What does the presence of hemoglobin in urine mean?

The presence of hemoglobin in the urine can signal various conditions, such as hemolytic anemia, blood disorders, or kidney damage. It suggests that red blood cells are being destroyed prematurely or that the kidneys are unable to properly filter the hemoglobin from the blood.

Q. What does a negative result mean?

A negative result means that no hemoglobin is detected in the urine, suggesting there is no immediate concern for hemoglobinuria or related conditions. However, further investigations may still be required if symptoms persist.

Q. How often should this test be done?

The frequency of this test is based on your individual health condition and symptoms. Follow your doctor’s instructions closely regarding the test frequency.

Q. Can I eat or drink before the test?

There are no specific dietary restrictions for the Hemoglobin Free, Urine test. However, it’s important to follow any instructions provided by your doctor especially if other tests are being conducted simultaneously.

Q. How are hematuria and hemoglobinuria different?

Hematuria is characterized by the presence of red blood cells in urine that can be observed under a microscope. Hemoglobinuria is indicated by the presence of heme in free form in the urine sample, usually detected by a chemical test or a dipstick analysis.

Q. How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
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Hemoglobin Free, Urine test price for other cities


Price inBangaloreRs. 189
Price inNew DelhiRs. 189
Price inNavi MumbaiRs. 189
Price inKolkataRs. 189
Price inAgraRs. 170
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