Double Marker Test- First Trimester in Surat
Understanding Double Marker Test- First Trimester in Surat
What is Double Marker Test- First Trimester in Surat?
A Double Marker Test- First Trimester is a prenatal screening test typically conducted between the 9th and 13th week i.e., the first trimester of pregnancy, and tells about the risk of specific chromosomal abnormalities, such as Down syndrome( Trisomy 21), Edwards’s syndrome (Trisomy 18) and neural tube defects (such as spina bifida) in the fetus. This test is available at an affordable price in Surat with Tata 1mg labs.
This test measures the levels of two biomarkers in the mother’s blood: human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). The levels of these markers, along with maternal age, gestational age, and ultrasound findings help determine the likelihood of chromosomal abnormalities in the fetus. These abnormalities can lead to various genetic conditions that can affect the baby’s growth and development. Therefore, their early detection is vital for ensuring comprehensive prenatal care and addressing potential health challenges effectively. No special preparation is required for this test.
What does Double Marker Test- First Trimester measure?
The test is named “Double Marker” or “Dual Marker” as it primarily focuses on two biomarkers associated with chromosomal abnormalities: free beta-hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein-A).
The placenta secretes free beta-hCG hormone during the pregnancy period. It helps provide nutrition to the developing fetus and can be detected in the blood 8-11 days after conception. Its levels continuously double every 48–72 hours, and peak levels can be seen during weeks 8–11 of gestation. Afterward, the HCG levels decrease and remain stable for the rest of the pregnancy. Higher than normal levels of this hormone after 11 weeks of gestation indicate the risk of Down syndrome.
PAPP-A is a protein produced by the placenta that is needed for the implantation and maintenance of a healthy placenta (afterbirth). Low levels of PAPP-A before the 14th week of pregnancy suggest an increased risk of fetal chromosomal abnormalities.