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Dengue Fever Antigen NS1, IgG & IgM

Dengue Fever Antigen NS1, IgG & IgM

Also referred as
Dengue profile
Dengue fever test
1,437+ booked recently
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Contains
3 tests
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A Dengue Fever Antigen NS1, IgG & IgM test plays a crucial role in diagnosing dengue, a viral infection caused by the dengue virus. This test measures the levels of the NS1 antigen and IgG and IgM antibodies in the blood. Together, they help determine the stage of infection, differentiate between recent and past infections, and aid in the appropriate and timely management of the infection.

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Understanding Dengue Fever Antigen NS1, IgG & IgM

Dengue is a viral infection caused by the dengue virus. The virus is transmitted to humans primarily through the bite of infected Aedes mosquitoes. It typically presents with a sudden onset of symptoms, including high fever, severe headache, pain behind the eyes, joint and muscle pain, rash, and mild bleeding. Early detection and differentiation are crucial, as secondary dengue infections can sometimes lead to more severe forms of the disease, such as dengue hemorrhagic fever or dengue shock syndrome. Upon infection, the dengue virus produces NS1 antigen protein during the early stages, and our immune system produces IgG and IgM antibodies in response to the virus. 

A Dengue Fever Antigen NS1, IgG & IgM test targets these different components of the immune response and the virus itself. The presence of NS1 antigen in the blood indicates an acute phase of infection (within the first few days of symptoms). It helps in early diagnosis, as it can be detected even before the body produces antibodies. IgM antibodies are the first type of antibodies produced by the immune system in response to a dengue infection. They typically appear within 3-5 days after the onset of symptoms and persist for about 2-3 months. Their presence suggests a recent dengue infection. Whereas, IgG antibodies develop later in the course of the disease and stay for an extended period. Their presence indicates a past dengue infection or immunity from a previous infection. However, rising IgG levels may indicate a secondary dengue infection.

Usually, no special preparation is required for a Dengue Fever Antigen NS1, IgG & IgM test; eat and drink as per your daily routine. Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. It is essential to interpret the results with clinical history, symptoms, and other laboratory findings to accurately assess the dengue infection status and formulate an overall treatment plan.

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What does Dengue Fever Antigen NS1, IgG & IgM measure?

Contains 3 tests

A Dengue Fever Antigen NS1, IgG & IgM test detects the NS1 protein of the dengue virus and the antibodies IgG and IgM produced by the body in response to the infection. 

The dengue NS1, also known as dengue nonstructural protein 1, is used to diagnose dengue fever early. This protein is secreted into the blood immediately after the infection; hence, it can be detected during the early stages of the infection. 

IgM antibodies are the first type produced by the immune system in response to a dengue infection. The IgM test helps identify recent or primary dengue infections, providing information about the active immune response. It is most accurate when performed a few days after the onset of symptoms. With time, IgM antibodies fall below detectable levels. 

IgG antibodies are produced more slowly in response to an infection. Levels of IgG rise with acute infection, stabilize, and persist for a more extended period. The IgG test helps identify past dengue infections and can help assess immunity. It may also be seen in the later stages of an acute infection.

The Dengue Fever NS1 Antigen test measures the NS-1 protein of the dengue virus. This protein is secreted into the blood during the infection; hence, it can only be detected during the early stages of the illness. It is recommended to do the Dengue Fever NS1 Antigen test in the first 5 days of fever. After 7-10 days of continuous fever, the recommended test is Dengue fever antibodies IgG & IgM.

Dengue fever may progress to dengue hemorrhagic fever or dengue shock syndrome if left untreated. Dengue hemorrhagic fever (DHF) includes variable manifestations like bleeding, vomiting blood, passing blood in the stool, difficulty breathing, and cold, clammy skin, especially in the extremities. If progressed, the virus may attack blood vessels, causing capillaries to leak fluid into the space around the lungs (pleural effusion) or the abdominal cavity (ascites).

Dengue shock syndrome (DSS) is a severe complication of dengue fever caused when the body's immune system overreacts to the dengue virus. It can lead to a sudden drop in blood pressure and dehydration; if not managed timely, it may lead to multiple organ failures. 

There is no specific treatment for dengue, but early diagnostic testing, such as the Dengue Fever NS1 Antigen test, can prevent the advancement of dengue to its complicated forms.

Know more about Dengue Fever NS1 Antigen

A Dengue Fever, IgG & IgM test measures two parameters in the blood: IgG and IgM antibodies. When a dengue infection occurs, IgM antibodies are the first line of defense, and detection of these antibodies is most effective when done at least 7–10 days after exposure. With time, IgM antibodies fall below detectable levels. IgG antibodies, however, are produced more slowly in response to the infection. Levels of IgG rise with acute infection, stabilize, and persist for a long time. 

Dengue fever is usually caused by the four dengue virus serotypes, with symptoms ranging from asymptomatic infection, undifferentiated fever, dengue fever (DF) to severe dengue hemorrhagic fever (DHF) with or without shock.

Dengue hemorrhagic fever (DHF) can go to a higher grade of fever. It might also include variable manifestations, like nose bleeding, vomiting blood, passing blood in the stool, breathing difficulty, cold, and clammy skin, especially in the extremities. During the second phase, the virus may attack blood vessels, causing capillaries to leak fluid into the space around the lungs (pleural effusion) or the abdominal cavity (ascites).

Dengue shock syndrome (DSS) is a severe complication of dengue fever caused when the body's immune system overreacts to the dengue virus. It can lead to a sudden drop in blood pressure and dehydration, and if not managed timely, it may lead to multiple organ failures. 

Know more about Dengue Fever, IgG & IgM

This further contains

  • Dengue Antibody, IgM
  • Dengue IgG Antibody

FAQs related to Dengue Fever Antigen NS1, IgG & IgM

A Dengue Fever Antigen NS1, IgG & IgM test is performed to detect and diagnose dengue fever by measuring the levels of the NS1 antigen, IgG antibodies, and IgM antibodies in the blood.
A Dengue Fever Antigen NS1, IgG & IgM test is usually performed within the first few days of symptom appearance to detect the NS1 antigen and IgM antibodies during the early stages of infection.
Combining results from NS1, IgM, and IgG tests helps the doctor distinguish between different stages of infection and assess the immune response. The presence of NS1 indicates active viral replication, IgM antibodies suggest a recent infection, and IgG antibodies indicate a previous infection or immunity.
A Dengue NS1 Antigen test helps to diagnose current dengue infection in the first week of illness. Whereas, a Dengue Antibody test, mainly IgG, detects the antibodies if the infection has occurred in the past two to three months.
The most common symptoms of dengue infection are high fever, headache, body aches, muscle and joint pain, pain behind the eyes, nausea, rash, and swollen glands. Sometimes, the infection may also remain asymptomatic (without symptoms).
Dengue fever can last up to 2–7 days after being bitten by an infected mosquito. However, most people recover after about a week.
In a primary dengue infection, the symptoms are typically mild. Whereas, a secondary dengue infection occurs when a person is infected a second time with a different strain of the virus and is often more severe than the first infection.
Rarely, some people who get sick with dengue may develop severe dengue fever which can result in shock, internal bleeding, organ failure, or even death. Severe dengue fever is life-threatening and needs medical interventions. If you have had dengue in the past, you are more likely to develop it. Infants and pregnant women are also at higher risk for developing severe dengue symptoms.
Coconut water, kiwi, apricot, orange, spinach, broccoli, date, walnuts, pomegranate, beetroot, papaya leaves, and whole grains can help increase platelet count in patients with dengue.
There is no specific treatment or antiviral medicine available for dengue. The available treatment is mainly supportive, which is based on observation of hemorrhagic and circulatory abnormalities and laboratory test results (for example, electrolytes, platelets, and hemoglobin).
Some easy steps and precautions may help to control dengue infection at home. Cover and clean water containers regularly, wear protective clothes, keep your house tidy and clean, dispose of water correctly, apply mosquito repellent, and invest in mosquito nets.
No, dengue fever is not contagious. Therefore, it cannot spread directly from person to person.
Content created by
Written by:
Dr. Lipika Khurana
BDS, PGDHHM
Reviewed by:
Dr. Swati Gupta (Anand)
MBBS, MD Lab Medicine
Want to know moreRead our editorial policy
Last Updated7th Oct 2025

Dengue Fever Antigen NS1, IgG & IgM test price for other cities

Price inBangaloreRs. 900
Price inHyderabadRs. 1710
Price inMumbaiRs. 1800
Price inPuneRs. 1800
Price inKolkataRs. 1889

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Package contains 3 tests
Dengue Fever NS1 Antigen
Dengue Fever, IgG & IgM (2)
Dengue Antibody, IgM
Dengue IgG Antibody