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CRP (C-Reactive Protein), Quantitative

Also referred as

CRP test

CRP blood test

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The CRP (C-Reactive Protein), Quantitative test is a simple blood test that measures the level of CRP, a protein produced by the liver, in the body. Usually, the CRP levels in the blood are low; however, these levels increase if you have inflammation. High CRP levels may indicate conditions like arthritis, infection, and injury.

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Understanding CRP (C-Reactive Protein), Quantitative

C-reactive protein (CRP) is an early inflammation or infection marker. This protein is produced in the liver and is usually found at concentrations lower than 10 mg/L in the blood. However, CRP levels rise rapidly within the first 6 to 8 hours during infectious or inflammatory disease states. When the inflammation or tissue injury subsides, CRP levels also decrease, making it a valuable marker for monitoring disease progression. The CRP (C-Reactive Protein), Quantitative test measures the level of CRP; however, it does not show the exact location or the possible cause of the inflammation.

Your doctor may advise the CRP (C-Reactive Protein), Quantitative test if you experience symptoms suggestive of inflammation, such as fever, chills, redness, swelling, nausea, vomiting, rapid breathing, and/or rapid heart rate. If you have a previously diagnosed inflammatory condition, this test helps monitor how your treatment works and whether the issue is adequately managed. Moderately to severely elevated CRP levels may be a sign of possible infections, particularly after surgery or in other inflammatory conditions such as rheumatoid arthritis, lupus, or inflammatory bowel disease (IBD). High levels of CRP may also be due to genetics, exposure to environmental toxins, the use of birth control pills, and during pregnancy.

No fasting is required for this test. You can eat and drink normally as per your routine. Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help them correlate your clinical and laboratory findings. The results will help the doctor determine your medical condition, make recommendations to manage your overall health, and formulate your treatment plan.

What does CRP (C-Reactive Protein), Quantitative measure?

The CRP test measures the levels of C-reactive protein in your body. This test helps detect the presence of inflammation in the body. It is a non-specific test as it cannot diagnose a condition by itself or determine its exact location or cause.

CRP is an acute phase reactant protein produced by the liver in response to an inflammation in the body. This inflammation may be due to tissue injury, infection, autoimmune diseases, or cancer. CRP levels are often increased before the onset of other symptoms of inflammation, such as pain, redness, fever, or swelling. These levels fall as the inflammation subsides.

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FAQs related to CRP (C-Reactive Protein), Quantitative

Why is the CRP (C-Reactive Protein), Quantitative test done?

The CRP test is done to measure the level of CRP (C-Reactive Protein) hormone that serves as an early marker of inflammation and infection.

Do I need to fast before taking the CRP (C-Reactive Protein), Quantitative test?

No fasting is required for this test. You can schedule it at your convenience without avoiding food or water beforehand.

What factors can affect the CRP levels in blood?

Blood CRP levels can be affected by certain medications, such as birth control pills, nonsteroidal anti-inflammatory drugs (NSAIDs), or hormone-replacement therapy (HRT); conditions like obesity, diabetes, pregnancy; or activities like smoking, alcohol consumption, heavy exercise, etc.

What is the meaning of high levels of CRP?

High levels of C-reactive protein may indicate arthritis, infection, or injury. Elevated levels may also be a sign of possible infections after surgery or other inflammatory conditions, such as rheumatoid arthritis, lupus, or inflammatory bowel disease (IBD). These high levels may also occur due to genetics, exposure to environmental toxins, the use of birth control pills, and during pregnancy. Consult your healthcare professional if your test results show high levels of CRP hormone.

What are the common symptoms of high CRP levels?

Some common symptoms of high CRP levels include pain, muscle weakness, stiffness or soreness, unexplained tiredness, low-grade fever, headaches, chills, insomnia, loss of appetite, and unexplained weight loss. However, if the CRP levels are severely increased, the person may experience severe headaches, body pain, sweating, chills or shaking, high-grade fever, persistent vomiting or diarrhea, breathing difficulty, rapid heart rate, severe muscle stiffness or soreness, etc.

What are chronic inflammatory diseases?

Chronic inflammatory diseases are conditions that lead to the development of long-lasting or frequently recurring inflammation, such as rheumatoid arthritis, lupus, and inflammatory bowel disease.

What treatment options are available if my C-reactive protein levels are high?

You may be able to lower your CRP levels by modifying your diet but will require medical assistance, such as statin drugs. However, if your CRP levels are high, consult your healthcare provider about the appropriate treatment options.

How can I naturally reduce my CRP levels?

Always consult your doctor if your CRP levels are high. However, some lifestyle modifications such as making healthy food choices, adding fiber- and vitamin-rich foods to your daily diet, exercising regularly to maintain healthy body weight, limiting alcohol intake and smoking, and managing stress may help reduce your CRP levels.

What additional tests can be prescribed by the doctor in case the result of the CRP test is not normal?

Additional tests that may be prescribed in case of abnormal CRP test results are the erythrocyte sedimentation rate (ESR) test, rheumatoid factor (RF) test, and anti-cyclic citrullinated peptide antibody (anti-CCP Antibody) test.

Content created by

Dr. Anupriya Nautiyal

MD Pathology, MBBS

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Last Updated

10th Oct 2025