Chimerism Pre Engraftment

Pre-engraftment chimerism refers to the presence of two distinct populations of cells with different genetic characteristics in a recipient's body before a hematopoietic stem cell or bone marrow transplant has fully engrafted. It typically indicates that the donor cells are beginning to establish themselves in the recipient's body. Monitoring pre-engraftment chimerism is essential in transplant medicine as it can provide insights into the progress of the transplant, predict potential complications, and help guide treatment decisions to ensure a successful outcome.