Test Detail
Overview
Interpreting Results

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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Lalit Mohan Gupta
MBBS, MD - Microbiology
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Complement 3

(C3)
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You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation required

Overview


What is C3?

It is usually ordered when you have recurrent infections usually with bacteria, unexplained edema, or any other symptoms related to autoimmune disorder like systemic lupus erythematosus (SLE). Sometimes, it is done periodically to help monitor a acute or chronic condition to predict the severity.

Why is C3 done?

  1. It may be ordered if you have unexplained edema, inflammation or symptoms of an auto immune disorder such as SLE 
  2. To monitor the severity of a complement deficiency disease 

Interpreting C3 results


Interpretations

  • Decreased C 3 levels are associated with increased risk of auto immune disorders like SLE, recurrent infections caused by fungi and parasites, hereditary angioedema, hepatitis, malnutrition, kidney diseases 
  • Complement proteins are increased in acute and chronic inflammation. Other common causes of increased complement activity are ulcerative colitis, thyroiditis, acute myocardial infarction, cancers like leukemia

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