Insulin - Fasting

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This test is for
Male, Female
Test Preparation
  1. Do not eat or drink anything other than water for 8-12 hours before the test.
Test Detail
Interpreting Results


What is Insulin-F?

Insulin is a hormone secreted by the beta cells of the pancreas. It helps to maintain normal blood glucose levels by regulating glucose uptake and storage by body cells. The Fasting Insulin Test measures the levels of insulin in blood after a fasting period.

Why is Insulin-F done?

The Fasting Insulin Test is performed:

·        To help determine the cause of low blood sugar (hypoglycemia)

·        To determine the proper production of insulin by the pancreas

·        To determine if insulin resistance in cells is the cause of hyperglycemia (high blood sugar)

·        To determine if insulin supplementation is necessary

·      To determine the presence of insulin-producing tumors (insulinomas) in the beta cells of the pancreas

What does Insulin-F Measure?

Carbohydrates consumed in the diet are digested and converted into the simple sugar, glucose. Glucose is absorbed by the cells for the production of energy, or stored in other forms like fats. Insulin is the hormone responsible for the uptake of glucose by the cells from blood for utilization and storage. It thus helps to maintain blood glucose levels within a normal range. Insulin also plays an essential role in the metabolism of lipids.

Levels of blood glucose and levels of insulin in blood maintain a balance with each other. A rise in blood sugar stimulates insulin production by the pancreas. This causes insulin levels to rise in blood. Insulin stimulates the uptake of glucose by cells, leading to a fall in blood glucose, and insulin levels in turn. Disruptions in this mechanism due to low insulin production by pancreas or inability of cells to respond to insulin (insulin resistance) cause a rise in blood sugar levels or hyperglycemia. Hyperglycemia is associated with diabetes. Diabetes Type 1 is an inherited condition where insulin is produced in insufficient quantities. Diabetes Type 2 occurs due to insufficient insulin production, or due to the development of insulin resistance. When cells are unable to respond to insulin, they cannot take up glucose from the blood effectively. The cells are deprived of glucose for energy, while glucose levels become high in the blood.

Insulin resistance increases with time. Increased glucose levels in blood stimulate the pancreas to produce excess insulin, leading to hyperinsulinemia (high insulin levels in the blood) along with hyperglycemia. Insulin resistance can also be seen in cases other than diabetes, such as prediabetes, polycystic ovarian syndrome (PCOS), pituitary or adrenal gland diseases, etc.

High insulin levels in the blood may also occur in patients suffering from tumors in the beta cells of pancreatic glands, or in cases of insulin overdose. Since excess insulin in these cases is not caused due to excess blood sugar levels, hyperinsulinemia in these cases can cause hypoglycemia (low blood sugar), leading to energy deprivation in all cells of the body.

Interpreting Insulin-F results


Normal range (Approx.): 2.0 - 25.0 uU/ml

Fasting Insulin Test is usually ordered with Fasting glucose test and the results interpreted as follows:

Fasting insulin level

Fasting glucose level






Normal or slightly high

Insulin Resistance



Insufficient insulin production, e.g., diabetes

Normal or high


Hypoglycemia due to over secretion of insulin

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Insulin-F

Frequently Asked Questions about Insulin - Fasting

Q. Can I do a home insulin test?
No, insulin test requires special instruments so, it can only be done in laboratories
Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle is used to withdraw blood from a blood vessel in your arm. The healthcare provider will tie an elastic band around your arm to make the blood vessels swell with blood. This makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution and then the needle is inserted into the blood vessel to collect the sample. You will feel a tiny pinprick during the procedure. Blood sample once collected will then be sent to the laboratory.
Q. Is there any preparation required before the Fasting Insulin Test?
A fasting period of 8 hours is prescribed before the test. Inform the doctor about any medications you may be taking. No other preparations are required unless specified by your doctor.
Q. Is there any risk associated with the Fasting Insulin Test?
There is no risk associated with the test. However, as this test involves a needle prick to withdraw the blood sample, in rare cases, a patient may experience excessive bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Q. What other tests can be prescribed by your doctor in case the results of Fasting Insulin Test is not normal?
Other tests that may be prescribed upon appearance of an abnormal result in the Fasting Insulin Test include: · Blood Glucose Tests · Proinsulin Test · C-Peptide Test · Cortisol Test · Plasma β-hydroxybutyrate (BHOB) Test
Q. What can cause high insulin levels in blood?
High levels of insulin may occur in blood due to: · Acromegaly · Obesity · Cushing syndrome · Certain medications like oral contraceptives, corticosteroids · Intolerance to fructose or galactose · Insulinomas · Insulin resistance as in Diabetes Type 2 · Administration of external insulin in excess dosage
Q. What can cause low insulin levels in blood?
Low levels of insulin may occur in blood due to: · Diabetes 1 and 2 · Hypopituitarism (low secretion of pituitary hormones) · Pancreatic diseases like pancreatitis, pancreatic cancer, etc.
Q. What are the common symptoms of hypoglycemia?
High insulin levels in blood without high sugar levels can lead to hypoglycemia or very low levels of glucose in blood. Symptoms of hypoglycemia that may appear include: · Sweating · Nausea · Weakness · Palpitations · Dizziness · Hunger · Trembling · Confusion · Irritability · Anxiety · Blurring vision · Irregular heartbeat · Seizures



Clinitech Laboratory Private Limited was registered at Registrar of Companies Mumbai on 19 March, 2010 and is categorised as Company limited by Shares and an Non-govt company. Clinitech Laboratory Private Limited's Corporate Identification Number (CIN) is U85195MH2010PTC201078 and Registeration Number is 201078. Clinitech Laboratory Private Limited registered address on file is AL - 1 / 545 & 546, SECTOR 16, AIROLI, NAVI MUMBAI MH 400708 IN, Navi Mumbai - 400708, Maharashtra, India. Clinitech...
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Virendra Jadhav
Booked test for mother who is about to undergo cataract ssurgery.Phlebo guys managed well in heavy rains.Report same day

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Content created by

Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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