Osmotic Fragility Test
What is Osmotic Fragility Test?
This assay is helpful in detecting or confirming mild spherocytosis and is used in suspected cases of Hereditary Spherocytic hemolytic anemia. Spherocytes are osmotically fragile cells that rupture more easily in hypotonic solutions. Patients with Immuno-hemolytic anemia or who have received recent blood transfusions may also show increased fragility.