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Thyroxine Binding Globulin

5490
4.2
NABL, CAP, ISO
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Overview
Interpretations
FAQ's
Thyroxine Binding Globulin

Overview of Thyroxine Binding Globulin

What is Thyroxine Binding Globulin?

Thyroxine Binding Globulin (TBG) test is done to assess the thyroid tissues. It helps in the diagnosis of other thyroid disorders such as hypothyroidism and hyperthyroidism. T3 (Triiodothyronine) and T4 (Thyroxine) hormones are produced by the thyroid gland which binds with the proteins produced by the body. However, small amounts of T3 and T4 remains ‘free’ as it does not bind with the proteins. The protein bound T3 and T4 binds to TBG. This test measures the levels of TBG which helps in assessing thyroid problems.

Sample Type

The sample type collected for Thyroxine Binding Globulin is: Blood

Preparation for Thyroxine Binding Globulin

  • No special preparation required

Why Get Tested for Thyroxine Binding Globulin?

  • To diagnose hypothyroidism (low levels of thyroid)

  • To diagnose hyperthyroidism (high levels of thyroid)

  • To monitor treatment in patients with thyroid disease

Understand more about Thyroxine Binding Globulin

TBG is a serum binding protein which has a high affinity to bind to T3 and T4. In the routine, the thyroid gland maintains the level of free hormone i.e. which is not bound to the TBG. This test is done to assess the thyroid tissues. It helps in diagnosing thyroid disorders such as hypothyroidism and hyperthyroidism. The rise in levels is associated with the intake of oral contraceptives or estrogen therapy. In conditions such as pregnancy or if a person has family history elevated levels of TBG are seen. The decrease in TBG levels is associated with intake of androgenic steroids, heavy doses of glucocorticoids, liver disease, nephrotic syndrome, congenital TGB variants and hypoproteinemic states.  


What Results of Thyroxine Binding Globulin mean?

Interpretations

High levels may indicate:

  • Liver disease

  • Acute intermittent porphyria

  • Hypothyroidism


Low levels may indicate:

  • Acromegaly

  • Acute illness

  • Hyperthyroidism

  • Malnutrition

  • Nephrotic Syndrome


Patient Concerns about Thyroxine Binding Globulin

Frequently Asked Questions about Thyroxine Binding Globulin

Q. What is Hyperthyroidism?
Hyperthyroidism is a condition in which the thyroid gland is overactive and there is an increased production of thyroid hormones by the thyroid gland. Causes of Hyperthyroidism include Graves’ disease, multinodular goiter, thyroid nodules, toxic adenoma, inflammation of the thyroid, eating too much iodine, and too much synthetic thyroid hormone. Diagnosis of this condition can help to relieve the symptoms and prevent long term complications.
Q. What is Hypothyroidism?
Hypothyroidism, also called underactive thyroid or low thyroid is a condition in which the thyroid gland does not produce enough thyroid hormones. It can be commonly caused by intake of low iodine diet or Hashimoto's thyroiditis (an autoimmune disease). Less common causes include previous treatment with radioactive iodine, injury to the pituitary gland which secretes TSH, intake of certain medicines, previous thyroid surgery or a lack of a functioning thyroid gland at birth.
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Provided By

NABL

CAP

ISO

We focus on providing patients quality diagnostic healthcare services in India. Through our network, we offer patients convenient locations for their diagnostic healthcare services and efficient service. With over 3368 diagnostic and related healthcare tests and services offered, we believe we are capable of performing substantially all of the diagnostic healthcare tests and services currently prescribed by physicians in India. Our key competitive strengths are: Business model focused on the patient as a customer and an established consumer healthcare brand associated with quality services, in a market where patients generally choose their diagnostic healthcare service provider. Well-positioned to leverage upon one of the fastest-growing segments of the Indian healthcare industry. A network whose growth yields greater economies of scale, combined with a hub and spoke model that is scalable for further growth. Centralized information technology platform that fully integrates our network and is scalable. Attractive financial performance, financial profile and return on invested capital. Experienced leadership team with strong industry expertise and successful track record. Some of our laboratories have achieved International Organization for Standardization, or ISO, certification for their quality systems. Our National Reference Laboratory has obtained ISO 9001:2008 certification (for the performance of routine and advanced diagnostic pathology testing services, including clinical trials), ISO 15189:2007 (for quality management in medical laboratories), ISO 15189:2012 certification (in the field of medical testing) and ISO 27001:2013 certification (for establishing an effective information management system that maintains and processes information security at our data center).
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