Teplizumab

INFORMATION ABOUT TEPLIZUMAB

Teplizumab Uses

Teplizumab is used in the treatment of Type 1 Diabetes Mellitus.

How Teplizumab works

Teplizumab is an antibody that partially blocks the immune system’s attack on insulin-producing cells of the pancreas. In this way, Teplizumab preserves insulin production and reduces the requirement for insulin therapy.

Common side effects of Teplizumab

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common

Lymphopenia, Rash, Decreased white blood cell count (lymphocytes), Headache

CONTENT DETAILS

Last updated

20 Feb 2025 | 05:01 AM (UTC)

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Medicine brands for Teplizumab

Expert advice for Teplizumab

Tell your healthcare provider if you have recently received or are scheduled to receive a vaccine. Teplizumab may affect the efficacy of the vaccine.
Inform the doctor if you are currently pregnant or planning a pregnancy or if you are breastfeeding.
Inform your doctor about an active or chronic infection or symptoms.
Your doctor may prescribe a few anti-nausea and pain-relieving medicines for the first few days of treatment to prevent symptoms such as headache, fever, muscle and joint pain, or nausea. These side effects are not commonly observed.

Frequently asked questions for Teplizumab

Q. How frequently do I need to take this medicine?

You will receive this medicine once a day, continuously for 14 days.

Q. What if I miss a scheduled dose?

If you miss a scheduled dose, your doctor will continue your treatment on the next scheduled day. You will not receive 2 doses on the same day.

Q. How is this medicine given?

Teplizumab is given an injection through the vein in your arm by a healthcare provider. Do not self-administer.

Q. What is the most important information I should know about this medicine?

Teplizumab may cause serious side effects, including muscle and joint pain, fatigue, nausea, headache, fever, decreased white blood cell count, and increased liver enzymes in the blood. Inform your doctor right away if you develop such signs and symptoms.

Q. How is Teplizumab available?

Teplizumab injection is available as a preservative-free, sterile, clear, and colorless solution in a 1 mg/mL single-dose vial. Teplizimab has been launched in the USA by the biopharmaceutical company Provention Bio, Inc. There is no information regarding its availability in India yet.