Serplulimab
Written By Dr. Sakshi Jain
Reviewed By Dr. Rajeev SharmaLast updated 09 Oct 2025 | 09:56 AM (UTC)
Serplulimab Uses
Serplulimab is used in the treatment of small cell lung cancer.
How Serplulimab works
Serplulimab works by helping the body’s own immune system fight cancer. Cancer cells often find ways to hide from immune defenses, but this medicine removes that shield, allowing immune cells to recognize and attack the cancer more effectively.
Common side effects of Serplulimab
Febrile neutropenia, Decreased white blood cell count (lymphocytes), Lymphopenia, Anemia (low number of red blood cells), Low blood platelets, Metabolic disorder, Decreased protein levels in blood, Increased liver enzymes, Electrolyte imbalance, Pneumonia, Urinary tract infection, Respiratory tract infection, Decreased appetite, Weight loss, Insomnia (difficulty in sleeping), Headache, Dizziness, Paresthesia (tingling or pricking sensation), Peripheral neuropathy (tingling and numbness of feet and hand), Cardiac adverse reactions, Cough, Gastrointestinal disorder, Rash, Hair loss, Dry skin, Skin hyperpigmentation, Musculoskeletal (bone, muscle or joint) pain, Injection site reactions (pain, swelling, redness)
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Expert advice for Serplulimab
- Monitor for immune-related adverse events while taking Serplulimab, especially pneumonitis, colitis, hepatitis, endocrinopathies, and skin reactions.
- It is important to report symptoms like shortness of breath, severe diarrhea, jaundice, or skin rash to your doctor.
- Delay or discontinue treatment if serious immune-related adverse events occur; corticosteroids may be needed.
- Avoid use of Serplulimab in pregnancy and breastfeeding unless benefits clearly outweigh risks.
Frequently asked questions for Serplulimab
It is usually given at regular intervals along with chemotherapy. The schedule is decided by your doctor.
No, it is approved for use in combination with chemotherapy for small cell lung cancer.
There is limited information, but patients planning a pregnancy should discuss options with their doctor before starting treatment.
You should always inform your doctor about all ongoing medicines to avoid harmful interactions.
Yes, regular blood tests and scans may be needed to monitor blood counts, liver function, thyroid function, and disease response.
Contact your doctor immediately to reschedule. Do not skip doses, as timely treatment is important for effectiveness.