Psoralen is used in combination with ultraviolet (UV) radiation for the treatment of psoriasis (skin condition that causes red, flaky patches of skin covered with silvery scales), eczema (a type of itchy skin rash), polymorphic light eruption (an itchy rash caused by sun exposure in people who are sensitive to sunlight) and mycosis fungoides (a certain type of cancer affecting skin).
How it works
Psoralen belongs to a class of drugs called furocoumarins. Psoralen makes skin much more sensitive to UV radiation, which exerts antiproliferative (slowing keratinization) and anti-inflammatory action on the skin and thereby curing inflammatory skin disorders.
Common side effects
Nausea, Nervousness, Pain, Acne, Depression, Dizziness, Headache, Insomnia, Itching, Skin redness, Swelling
• Always take psoralen tablets 2 hours before the UV radiation exposure along with food or milk.
• Take a plain shower before your treatment to keep your skin clean and dry.
• Do not use perfumes, aftershave, deodorants or other cosmetics and toiletries as they make your skin even more sensitive to the UV light causing blistering of your skin.
• Never take psoralen more than the dose that has been prescribed as it may cause burning or blistering of your skin after exposure to UV light.
• Avoid any other form of artificial UV treatment or relaxation e.g. solarium or sunbathing.
• Men should take the required precautions to protect the genital area.
• Always wear protective goggles while receiving your light dose in the cabinet.
• UV400 standard eye protection glasses and protective skin covering must be worn for 24 hours from time of taking psoralen tablets.
• Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
• Should not be given to patients who are allergic to psoralen or any of its ingredients.
• Should not be given to children under 14 years of age.
Frequently asked questions
Q. What is PUVA therapy?
Psoralen and ultraviolet A radiation (PUVA therapy) is used to treat certain skin conditions like psoriasis, eczema, polymorphic light eruption, and mycosis fungoides.