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Medroxyprogesterone is used in abnormal uterine bleeding and amenorrhea (absence of menses)

How it works

Medroxyprogesteone is one of a group of medicines called ‘progestogens’ which act like progesterone, a natural sex hormone. It can slow down the growth of certain tumors which are sensitive to hormones. As a contraceptive, it acts by preventing an egg being from fully developed and released from the ovaries, changes the lining of your womb and thickens the mucus at the entrance of the womb which makes pregnancy less likely to occur.

Common side effects

Headache, Nausea, Vomiting, Abdominal pain, Breast pain, Mood changes, Irregular menstrual cycle

Available Medicine

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Expert advice

  • Swallow each tablet whole. Take your tablets at the same time each day. Treatment may be required for 8 to 10 weeks before any effect can be found.
  • Do not take medroxyprogesterone If you are hypersensitive (allergic) to medroxyprogesterone or other similar hormone  medicines or any of the other ingredients of this medicine.
  • Avoid smoking while you are taking this medicine. Smoking greatly increases your risk of blood clots.
  • This medicine can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). Patients and caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
  • Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
  • Avoid becoming pregnant while being treated with medroxyprogesterone.

Frequently asked questions


Q. Is medroxyprogesterone a hormone/ bioidentical hormone/ a steroid?
Medroxyprogesterone is a steroid, synthetic, a non-bio-identical hormone

Q. Does medroxyprogesterone work?
It does work well for most of the people if taken at recommended dosage and duration

Q. Can i take ibuprofen/ Tylenol/ birth control pill with medroxyprogesterone?
There are no interactions reported when medroxyprogesterone is taken with ibuprofen or Tylenol. However, it does not mean it does not exist. Always consult your doctor before using it

Q. Does medroxyprogesterone cause ovulation/stop ovulation?
Medroxyprogesterone will not cause ovulation

Q. Does medroxyprogesterone expire?
Like any other medicine, medroxyprogesterone also have an expiry date.

Content on this page was last updated on 17 January, 2017, by Dr. Varun Gupta (MD Pharmacology)