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Empagliflozin + Sitagliptin

Written By Dr. Lipika KhuranaReviewed By Dr. Mekhala Chandra
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Empagliflozin + Sitagliptin Uses

Empagliflozin+Sitagliptin is used in the treatment of type 2 diabetes mellitus.

How Empagliflozin + Sitagliptin works

Empagliflozin + Sitagliptin is a combination of two medicines, empagliflozin and sitagliptin, which help control blood sugar levels in people with type 2 diabetes. Empagliflozin works by helping the kidneys remove extra sugar from the body through urine. Sitagliptin helps the body release more insulin when blood sugar is high and reduces the amount of sugar made by the liver. By working in different ways, these two medicines complement each other and provide better blood sugar control than either medicine alone.

Common side effects of Empagliflozin + Sitagliptin

Urinary tract infection, Fungal infection, Upper respiratory tract infection, Headache
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Expert advice for Empagliflozin + Sitagliptin

  • Let your doctor know if you are taking any other diabetes medicines with Empagliflozin + Sitagliptin, especially insulin or sulfonylureas, to avoid the risk of hypoglycemia (low blood sugar).
  • Do not stop taking Empagliflozin + Sitagliptin suddenly without consulting your doctor, even if you feel well or your blood sugar improves.
  • If you plan to undergo surgery or any major procedure, inform your doctor in advance, as temporary discontinuation may be advised.
  • Empagliflozin + Sitagliptin is not suitable for people with type 1 diabetes or the treatment of diabetic ketoacidosis.

Frequently asked questions for Empagliflozin + Sitagliptin

No, you should not stop taking Empagliflozin+Sitagliptin without your doctor’s advice. Type 2 diabetes is a long-term condition that requires ongoing treatment, even if your sugar levels improve.
A healthy, balanced diet is important for managing diabetes. Your doctor or dietitian may suggest specific dietary changes to get the best results from Empagliflozin+Sitagliptin.
Yes, it may be prescribed along with other diabetes medicines, but your doctor will decide the best combination based on your condition and response to treatment.
Yes, especially empagliflozin, which increases urination. Drink enough fluids throughout the day to stay hydrated and avoid dizziness or low blood pressure.