Empagliflozin + Linagliptin + Metformin

Written By Dr. Subita Alagh

Reviewed By Dr. Mekhala Chandra

Last updated 25 Nov 2025 | 09:37 AM (UTC)

Empagliflozin + Linagliptin + Metformin Uses

Empagliflozin+Linagliptin+Metformin is used in the treatment of type 2 diabetes mellitus.

Available generics for Empagliflozin + Linagliptin + Metformin

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Empaneo LM 25mg/5mg/1000mg Tablet

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How Empagliflozin + Linagliptin + Metformin works

Empagliflozin + Linagliptin + Metformin is a combination of three medicines: empagliflozin, linagliptin, and metformin hydrochloride. Empagliflozin works by blocking a protein in the kidneys called SGLT2 (sodium-glucose cotransporter 2), which normally reabsorbs sugar back into the blood. Empagliflozin blocks this protein, allowing more sugar to be removed from the body through urine. Linagliptin targets an enzyme called DPP-4 (dipeptidyl peptidase-4), which breaks down hormones that help the pancreas release insulin and lower sugar levels after meals. Metformin hydrochloride reduces the amount of sugar produced by the liver and helps the body respond better to insulin. Together, they control blood sugar from multiple angles, leading to more stable glucose levels and reduced risk of complications related to type 2 diabetes.

Common side effects of Empagliflozin + Linagliptin + Metformin

Upper respiratory tract infection, Constipation, Urinary tract infection, Headache, Nasal congestion (stuffy nose), Sore throat, Gastroenteritis, Diarrhea

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Medicine brands for Empagliflozin + Linagliptin + Metformin

MSN Laboratories Private Limited

₹212 to ₹212

1 variant(s)

Emnorm LM

Ipca Laboratories Ltd

Eris Lifesciences Ltd

Intas Pharmaceuticals Ltd

₹139 to ₹139

1 variant(s)

Linaxa EM

Torrent Pharmaceuticals Ltd

₹173 to ₹195

2 variant(s)

Empha LM

Intas Pharmaceuticals Ltd

Expert advice for Empagliflozin + Linagliptin + Metformin

Take Empagliflozin + Linagliptin + Metformin at the same time each day. Set a daily reminder or alarm to avoid missing doses.
Call your doctor if you feel very weak, confused, or have trouble breathing while taking Empagliflozin + Linagliptin + Metformin. These may be signs of serious side effects needing urgent care.
Drink enough fluids daily unless your doctor advises otherwise. Aim for at least 6–8 glasses of water a day to prevent dehydration.
Inform your doctor before any planned surgeries or contrast imaging tests. You may need to stop Empagliflozin + Linagliptin + Metformin temporarily to prevent kidney problems.
Carry a source of fast-acting sugar like glucose tablets or candy. Use it immediately if you feel dizzy, sweaty, shaky, or confused.

Frequently asked questions for Empagliflozin + Linagliptin + Metformin

Q. Is Empagliflozin+Linagliptin+Metformin treatment for type 1 diabetes?

No. Empagliflozin+Linagliptin+Metformin is not approved for treating type 1 diabetes or diabetic ketoacidosis. Follow your doctor’s instructions and do not take the medicine for these conditions.

Q. Can Empagliflozin+Linagliptin+Metformin replace diet and exercise?

No. It should be used along with healthy eating and regular physical activity as recommended by your doctor.

Q. Is Empagliflozin+Linagliptin+Metformin safe during pregnancy or breastfeeding?

No. Empagliflozin+Linagliptin+Metformin is not recommended during pregnancy or while breastfeeding due to potential risks to the baby.

Q. Can older adults take Empagliflozin+Linagliptin+Metformin?

Yes, but with caution. Older adults may have a higher risk of dehydration and kidney issues, so monitoring is essential.

Q. Are there foods or drinks that I should avoid?

Yes. Avoid excessive alcohol intake, which can increase the risk of serious side effects like lactic acidosis.

Q. Does Empagliflozin+Linagliptin+Metformin interact with other medications?

Yes. Empagliflozin+Linagliptin+Metformin can interact with drugs affecting kidney function or blood sugar. Always inform your doctor of all the medications you take.

Q. Will I need any tests while taking Empagliflozin+Linagliptin+Metformin?

Yes. Your doctor may monitor kidney function, blood sugar levels, and vitamin B12 levels during treatment.