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Diosmin is used in combination with hesperidin to treat diseases caused due to inadequate blood flow through the veins (chronic venous insufficiency) such as piles (hemorrhoids) and varicose veins (enlarged and twisted veins). It is also used to relieve conditions with poor circulation in the legs, painful, heavy and restless leg at bedtime, leg ulcers and for improving lymphatic drainage (a technique that stimulates the lymphatic system and encourages the flow of lymph fluid).

How it works

Diosmin belongs to a class of drugs called flavonoids. It works by dilating the blood vessels and causing a decrease in blood pressure in the veins. Diosmin also decreases swelling and inflammation by reducing levels of some chemicals (prostaglandins) that cause inflammation, thereby restoring normal vein function. 

Common side effects

Abdominal pain, Diarrhoea, Headache


Expert advice

• Always follow the instructions of doctor regarding the dosage and duration.
• Chronic venous insufficiency, chronic hemorrhoids and leg ulcers: 500 mg twice daily. 
• Acute hemorrhoidal attacks: 3 g once daily for 4 days followed by 2 g per day for 3 days. 
• Internal hemorrhoids: 1.5 g twice daily for 4 days followed by 1 g twice daily for 3 days
• Do not take diosmin for more than three months.
• Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.

Frequently asked questions


 Q. Is diosmin a blood thinner?
Diosmin acts by dilating the blood vessels, especially veins. It is not known to be used as a blood   thinner.
Q. What is diosmin hesperidin?
Diosmin is usually available as a fixed dose combination with hesperidin.
Q. Does diosmin lower or raise blood pressure or cause constipation?
Though, diosmin acts by dilating the blood vessels, it is not known to lower or raise blood vessels. 
Q. Does diosmin cause constipation?
Diosmin may cause diarrhea, but is not known to cause constipation. Do consult your doctor for any complaints.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)