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Information about Cyclophosphamide

Cyclophosphamide Uses

Cyclophosphamide is used in the treatment of cancer and nephrotic syndrome.

How Cyclophosphamide works

Cyclophosphamide is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

Common side effects of Cyclophosphamide

Hair loss, Decreased white blood cell count (neutrophils), Vomiting, Nausea, Diarrhea, Infection, Myelosuppression, Decreased white blood cell count (lymphocytes), Cystitis, Microhematuria
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Reviewed By
MD (Pharmacology), MBBS
Last updated
13 Jun 2023 | 11:25 AM (UTC)

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Available Medicine for Cyclophosphamide

Endoxan NZydus Cadila
72 to ₹2803 variant(s)
CycloxanBiochem Pharmaceutical Industries
44 to ₹1682 variant(s)
CyclocelCelon Laboratories Ltd
35 to ₹1133 variant(s)
EndoxanZydus Cadila
43 to ₹1746 variant(s)
ChophosIntas Pharmaceuticals Ltd
45 to ₹1503 variant(s)
PhosmidNeon Laboratories Ltd
25 to ₹794 variant(s)
OncomideKhandelwal Laboratories Pvt Ltd
16 to ₹993 variant(s)
UniphosUnited Biotech Pvt Ltd
30 to ₹1073 variant(s)
CydoxanAlkem Laboratories Ltd
681 variant(s)
OncophosCadila Pharmaceuticals Ltd
35 to ₹1123 variant(s)

Expert advice for Cyclophosphamide

  • Cyclophosphamide helps in the treatment of cancer.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Take it with food if you experience irritation of the stomach, preferably in the morning.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Cyclophosphamide if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.

Frequently asked questions for Cyclophosphamide


Q. Can Cyclophosphamide cause infertility?

Yes, Cyclophosphamide can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Cyclophosphamide.

Q. Do I need to avoid sun exposure during treatment with Cyclophosphamide?

No, there is no evidence that you need to avoid sun exposure while on Cyclophosphamide. Skin and nail discoloration are reported rarely with Cyclophosphamide.

Q. Can Cyclophosphamide cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cyclophosphamide is high in the urinary bladder. Other rare cancers that may occur with use of Cyclophosphamide include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Is Cyclophosphamide chemotherapy medicine?

Yes, Cyclophosphamide is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Q. Can Cyclophosphamide be used for non-cancer condition?

Yes, Cyclophosphamide can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cyclophosphamide for nephrotic syndrome has not been established.

Q. Can Cyclophosphamide causes weight loss?

Yes, Cyclophosphamide may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.


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