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    Information about Cefotaxime

    Cefotaxime uses

    Cefotaxime is used in the treatment of bacterial infections. It is used for short-term treatment of bacterial infections of urinary tract, skin and soft-tissue, ear, bone, blood, abdomen, genital and lungs (pneumonia). It is also used to prevent infections after surgery.

    How cefotaxime works

    Cefotaxime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body.

    Common side effects of cefotaxime

    Nausea, Diarrhoea, Allergic reaction

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    Expert advice for Cefotaxime

    • Your doctor has prescribed Cefotaxime to cure your infection and improve symptoms.
    • Do not skip any doses and finish the full course of treatment even if you feel better.
    • Discontinue Cefotaxime and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
    • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
    • If you're on blood thinners, Cefotaxime can interact with your medications and increase your bleeding tendencies.

    Frequently asked questions for Cefotaxime


    Q. Is cefotaxime a sulfa, penicillin or broad spectrum antibiotic?

    Cefotaxime does not contain sulfa and is not a penicillin drug. It is a third generation, broad spectrum cephalosporin antibiotic

    Q. Is cefotaxime compatible with potassium and TPN?

    Yes, cefotaxime can be given with potassium and TPN (total parenteral nutrition)

    Q. Is Cefotaxime ototoxic (toxic to the ear)?

    No, Cefotaxime is not an ototoxic drug when given alone, but when given along with aminoglycoside antibiotics (gentamicin, tobramycin), it may increase ototoxicity

    Q. Is Cefotaxime bacteriostatic or bactericidal?

    Cefotaxime is a bactericidal agent

    Q. What organisms does Cefotaxime cover?

    Cefotaxime is active against Escherichia coli, group A and B streptococci, pseudomonas and staphylococcus bacteria. In some cases, Streptococcus pneumonia may show resistance to the drug. It may not be effective against methicillin- resistant Staphylococcus aureus (MRSA).

    Content on this page was last updated on 15 December, 2017, by Dr. Varun Gupta (MD Pharmacology)