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Buclizine in combination with paracetamol and codeine is used for the short term treatment of acute moderate pain in migraine (headache, nausea and vomiting), which is not relieved by paracetamol, ibuprofen, or aspirin alone. It can also be used in certain allergic conditions like urticaria (allergic itching and swelling of skin).

How it works

Buclizine belongs to group of medicines called antihistaminics. It inhibits the action of chemicals called histamines in the body, thereby reducing the allergic reactions. By acting on brain, it causes sedation and reduces symptoms of nausea and vomiting.

Common side effects

Psychomotor impairment, Blurred vision, Dizziness, Dry mouth, Difficulty in urination, Eye swelling, Lip swelling, Gastrointestinal discomfort, Headache, Rash, Skin redness, Sleepiness, Thickened respiratory tract secretions, Urticaria


Expert advice

  • Consult your doctor if you have closed angle glaucoma (increased pressure in the eyes), liver or kidney disease, if you are taking monoamine oxidase inhibitors (drugs for depression)
  • You should not take buclizine for more than 3 days.
  • Do not drive or operate heavy machinery because you may feel sleepy or dizzy while being treated with buclizine. 
  • Do not consume alcohol while taking buclizine as it may worsen the side effects.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions


Q. What is buclizine hydrochloride (Hcl) multivitamins?
Salt form of buclizine (buclizine Hcl) along with multivitamins is used in the patients with low appetite and as dietary support in chronic illness, metabolic disorders and during recovery from medical treatment or post-surgery. It is also used as supplementary treatment for anorexia (loss of appetite) associated with tuberculosis, iron-deficiency anemia, anorexia nervosa (loss of appetite for food) and malnutrition (lack of proper nutrition).
Q. What is buclizine syrup?
Buclizine syrup is used as an appetite stimulant for weight gain in children.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)