Brolucizumab
Information about Brolucizumab
Brolucizumab Uses
Brolucizumab is used in the treatment of wet age-related macular degeneration, cancer of colon and rectum, non-small cell lung cancer, ovarian cancer, cancer of fallopian tube and kidney cancer.
How Brolucizumab works
Vascular endothelial growth factor (VEGF) is a protein that promotes the growth of new blood vessels. In certain eye diseases, abnormal blood vessels start growing under the retina, leading to fluid leakage, bleeding, and damage to the central part of the retina called the macula. This can result in severe vision loss and distortion of central vision. Brolucizumab blocks the activity of the VEGF protein. By inhibiting VEGF, the medication reduces the growth and leakage of abnormal blood vessels in the retina.
Common side effects of Brolucizumab
Retinal hemorrhage (bleeding), Uveitis, Eye pain, Reduced visual acuity, Blurred vision, Increased intraocular pressure, Corneal abrasion, Vitreous floaters, Iridocyclitis, Iritis (inflammation of the middle layer of the eye), Retinal vascular disease, Vitreous haemorrhage, Vitreous detachment, Cataract, Conjunctival hemorrhage, Punctate keratitis
Available Medicine for Brolucizumab
PagenaxNovartis India Ltd
₹355651 variant(s)
Expert advice for Brolucizumab
- Brolucizumab is administered by a qualified ophthalmologist or retina specialist.
- Inform your eye doctor immediately if you experience any signs of infection, such as redness, pain, or discharge from the eye.
- If you experience symptoms of an allergic reaction, such as hives, itching, swelling, or difficulty breathing, seek immediate medical attention.
- Inform your eye doctor if you have a history of glaucoma or elevated intraocular pressure (IOP), as this may influence treatment decisions.
- Inform your eye doctor immediately if you notice any sudden changes in vision or experience flashes of light.
- Inform your eye doctor if you experience eye pain, redness, or sensitivity to light.
- Brolucizumab is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
- Brolucizumab is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
- It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
- It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
- Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Brolucizumab.