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Amphotericin B Topical



Amphotericin B topical is used to treat fungal infections of the skin, nail, hair (superficial mycoses) and eyes. 

How it works

Amphotericin B belongs to a class of medications called as antifungal agents. It works by interfering with the formation of the fungal cell membrane and weakening it thereby killing the sensitive fungi.

Common side effects

Burning sensation, Itching, Contact sensitization, Dry skin, Skin redness


Expert advice

  • Inform your doctor immediately if skin problem does not improve or worsens within 1 to 2 weeks.
  • To avoid relapse, continue use of topical amphotericin B even if symptoms begin to clear up.
  • Avoid direct contact of the cream or ointment with your eyes. In case of direct contact, wash your eyes with water and seek immediate medical attention.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Do not use if you are allergic to amphotericin B or any of its ingredients. 

Frequently asked questions

Amphotericin B Topical

Q. Is amphotericin B an antibiotic?
Yes, amphotericin B is an antifungal antibiotic for the treatment of serious infections caused by fungi.
Q. Is amphotericin B fungistatic or fungicidal?
Amphotericin B is fungicidal in nature, it acts by killing the fungus.
Q. Is amphotericin B testing dose needed?
Yes, amphotericin B is associated with allergic (severe and serious) reaction, therefore it is recommended to apply a test dose before starting the therapy to check for sensitivity. 
Q. Is amphotericin B light sensitive?
Amphotericin B is not light sensitive.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)