Alogliptin + Metformin

Information about Alogliptin + Metformin

Alogliptin + Metformin Uses

Alogliptin+Metformin is used in the treatment of type 2 diabetes mellitus.

How Alogliptin + Metformin works

Alogliptin + Metformin is a combination of two antidiabetic medicines, alogliptin and metformin. Alogliptin works by increasing the release of insulin from the pancreas and decreasing the hormones responsible for raising blood sugar levels. Metformin limits the absorption of glucose from food and reduces the production of glucose by the liver. Metformin also increases the body's response to insulin.

Common side effects of Alogliptin + Metformin

Upper respiratory tract infection, Nasopharyngitis (inflammation of the throat and nasal passages), Diarrhea, High blood pressure, Headache, Back pain, Urinary tract infection, Nausea, Vomiting, Flatulence, Weakness, Indigestion, Abdominal discomfort, Decreased appetite, Decreased creatinine clearance, Increased lipase in the blood
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MMST, MBBS
Reviewed By
MBA, MBBS
Last updated
05 Sep 2023 | 09:48 AM (UTC)

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Available Medicine for Alogliptin + Metformin

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Expert advice for Alogliptin + Metformin

  • Take Alogliptin + Metformin after a meal or with a snack, as this will reduce the chance of an upset stomach.
  • Alogliptin + Metformin may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, and tremor.
  • It is important that you take care of the skin on your lower limbs and report any sores or signs of infection to your doctor.
  • You should let your doctor know if you get unusually thirsty, pass urine more frequently, and feel tired. These are signs of too much sugar in your blood, and your dose may need adjusting.
  • Monitor your blood sugar regularly while taking this medicine.
  • Inform your doctor immediately if you experience rapid or deep breathing, muscle pain, fatigue, and drowsiness.
  • Lifestyle changes, like a low-sugar diet, exercise, losing weight, not smoking, and reducing the amount of alcohol you normally drink, may help this medication work better.

Frequently asked questions for Alogliptin + Metformin

Alogliptin + Metformin

Q. What is the dosage of Alogliptin+Metformin?

This medicine should be taken twice daily with food with a gradual increase in the dose to lower your chances of an upset stomach. However, it is advisable to always consult your doctor before taking it.

Q. Is Alogliptin+Metformin safe for kidneys?

Alogliptin+Metformin does not cause kidney damage. The kidneys process and clear the drug out of your system via urine. However, if your kidneys are not functioning properly, this medicine can lead to a condition called lactic acidosis. Symptoms of lactic acidosis include tiredness, weakness, muscle pain, sleepiness, abdominal pain, and breathing problems.

Q. Can Alogliptin+Metformin cause dizziness?

Yes, Alogliptin+Metformin can cause dizziness as a side effect. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while traveling.

Q. Can this medicine be used to treat type 1 diabetes?

This medication does not treat type 1 diabetes or diabetic ketoacidosis (increased ketones in the blood or urine).

Q. Can Alogliptin+Metformin cause severe skin reaction?

This medicine may cause a skin reaction called bullous pemphigoid which may require hospitalization. Tell your doctor right away if you develop blisters or skin peeling. You may be advised to stop the treatment.

Q. Can Alogliptin+Metformin cause pancreatitis?

There are reports of acute pancreatitis due to Alogliptin+Metformin. Patients are prompted to discontinue this medicine and contact their doctor if there is persistent severe abdominal pain, sometimes radiating to the back.

Q. What should you not eat while taking Alogliptin+Metformin?

It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar.

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