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Rituximab

Written By Dr. Anuj SainiReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Rituximab Uses

Rituximab is used in the treatment of non-Hodgkin lymphoma (NHL), blood cancer (chronic lymphocytic leukemia), rheumatoid arthritis, granulomatosis with polyangiitis and microscopic polyangiitis.

How Rituximab works

Rituximab is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.

Common side effects of Rituximab

Headache, Weakness, Infection, Chills, Decreased white blood cell count (neutrophils), Fever, Infusion site reaction, Lymphopenia, Abdominal pain, Back pain
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Expert advice for Rituximab

  • It is given as a drip (intravenous infusion) by your doctor or nurse.
  • You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
  • Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Inform your doctor  if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.