Tianeptine
Written By Dr. Swati MishraLast updated 25 Nov 2025 | 09:34 AM (UTC)
Tianeptine Uses
Tianeptine is used in the treatment of depression, Anxiety, bed-wetting, obsessive-compulsive disorder, insomnia and neuropathic pain. It is used in patients intolerant of or unresponsive to other treatment options for depression.
How Tianeptine works
Tianeptine is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Common side effects of Tianeptine
Sleepiness, Headache, Dizziness, Muscle pain, Insomnia (difficulty in sleeping), Decreased appetite, Tachycardia, Weakness
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Read Our Editorial PolicyMedicine brands for Tianeptine
StabLON
Servier India Private Limited
₹158 to ₹158
1 variant(s)
Tynept
Intas Pharmaceuticals Ltd
₹153 to ₹414
2 variant(s)
Eason
Alde Medi Impex Ltd
₹131 to ₹131
1 variant(s)
Tipene
Westin Pharmaceuticals Pvt. Ltd
₹130 to ₹130
1 variant(s)
Tiatol
Colgen Pharma
₹112 to ₹112
1 variant(s)
Tiazac
Ryon Pharma
₹105 to ₹287
2 variant(s)
Stabnodep
Lifecare Neuro Products Limited
₹121 to ₹121
1 variant(s)
Anept
Consern Pharma Limited
₹150 to ₹150
1 variant(s)
Tiaptin
Kriven Health Solutions
₹154 to ₹154
1 variant(s)
Tinetin
Vega Biotec Pvt. Ltd
₹103 to ₹103
1 variant(s)
Expert advice for Tianeptine
- It may take 4 to 6 weeks for Tianeptine to start working. Keep taking it as prescribed.
- It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Tianeptine as it may cause excessive sleepiness.
- Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
- It may cause a sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking medicine without talking to your doctor first.
- The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
- It can take 2 to 3 weeks for Tianeptine to start working.
- You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
- If your doctor asks you to stop Tianeptine, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
- Avoid driving or operating machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Tianeptine, as it may cause excessive drowsiness and calmness.
- The addiction/dependence potential of Tianeptine is very less.
- It may be extremely dangerous in overdose.
Frequently asked questions for Tianeptine
Tianeptine belongs to a group of medicines known as antidepressants, used to treat depression. It works by restoring the chemical imbalance in the brain which helps to improve mood and behavior.
Yes, Tianeptine is effective if taken in the dose and duration prescribed by the doctor. Avoid skipping doses and tell your doctor if you experience any side effects while taking Tianeptine. The doctor may suggest ways to manage or prevent them. It may take a few weeks for you to see improvement in your symptoms. However, the treatment may be continued for a few months for effective management of your condition.
If you have missed a dose of Tianeptine, take it as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and take it in the regular schedule. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Tianeptine may cause side effects such as increased heart rate, blurred vision, dryness in mouth, difficulty in urination, weight gain, constipation and orthostatic hypotension (sudden lowering of blood pressure on standing). Consult your doctor if any of these side effects do not go away or worry you.
No, do not stop the medication abruptly even if you are feeling good as it may worsen your condition. Continue taking Tianeptine for the duration prescribed by your doctor to get maximum benefit. Consult your doctor if the side effects bother you or if you have completed your course of treatment. The doctor will suggest gradual dose reduction before taking you off this medicine completely.
Do not take Tianeptine during pregnancy unless recommended by the doctor. It is given only if the benefits are clearly more than the risks involved. This is because studies have shown significant risks to the developing baby. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors and spasms.. Hence, it is advised that you should consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding.
Yes, Tianeptine may make you feel sleepy. Therefore, it is advised that you should not drive, use any heavy machinery or do any work that requires concentration while taking Tianeptine. Also, avoid taking alcohol if you are being treated with Tianeptine as it will only increase your drowsiness.
Before taking Tianeptine, you should tell your doctor if you are allergic to Tianeptine or any of its ingredients to avoid any allergic reactions. Inform your doctor if you have any problems with your heart, liver, thyroid, prostate or kidneys. Also tell your doctor if you have or ever had epilepsy (seizures or fits), diabetes, or glaucoma. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Also, inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.



