Peridol

Peridol Injection is a long‑acting antipsychotic injection given into the muscle to treat schizophrenia in people who need ongoing, monthly treatment to help prevent symptom relapses.

Individuals should not use Peridol Injection if they have Parkinson’s disease, dementia with Lewy bodies, a severe allergy to haloperidol, or severe central nervous system depression/coma. It must not be given into a vein.

While on Peridol Injection treatment, cases of sudden death, dangerous heart rhythm changes (QTc prolongation), and a rhythm called torsades de pointes have been reported. Risk is higher with high doses, low potassium or magnesium, existing heart problems, thyroid issues, or when used with other QT‑prolonging medicines.

Yes, tardive dyskinesia (uncontrolled, possibly permanent movements) can happen from Peridol Injection use, especially with longer use and higher total doses. Doctors aim for the lowest effective dose and regularly reassess the need for ongoing treatment.

Peridol Injection can cause neuroleptic malignant syndrome (NMS), which is a rare, life‑threatening reaction with very high fever, severe muscle stiffness, confusion, unstable heart rate or blood pressure, and possible kidney injury. Treatment requires stopping Peridol Injection and urgent hospital care.

Low white blood cells (including severe neutropenia), liver injury (including acute liver failure, hepatitis, jaundice), and blood abnormalities have been reported with Peridol Injection use. Doctors may monitor blood counts and liver tests and stop treatment if serious changes occur.

During Peridol Injection treatment, severe chest pain or fainting, very fast or irregular heartbeat, severe dizziness, uncontrollable muscle movements, very high fever with rigidity, trouble breathing or swelling of face/throat, or severe allergic rash/peeling skin should be treated as emergencies.