Olkem Trio

Side Effects of Olkem Trio are Headache, Dizziness, Back pain, Nausea, Abdominal pain, Fatigue, Diarrhea, Increased triglyceride level in blood, Increased uric acid level in blood, Bronchitis (inflammation of the airways), Cough, Joint inflammation, Gastroenteritis, Dyspepsia, Skeletal pain, Blood in urine, Urinary tract infection, Urticaria, Skin rash, Peripheral edema, Increased sodium level in blood, Increased glucose level in blood, Decreased potassium level in blood, Postural hypotension (low blood pressure), Loss of appetite, Increased liver enzymes, Increased blood urea, Increased creatine phosphokinase (CPK) level in blood, Impotence.

Severe

Side Effects of Olkem Trio are Taste change, Chest pain, Rash, Facial swelling, Skin peeling, Hair loss, Erythema multiforme, Papules, Eye disorder, Dry skin, Muscle stiffness, Disorientation, Epigastric pain, Liver dysfunction, Electrolyte imbalance, Difficulty in swallowing, Increased levels of blood fat, Respiratory failure, Red blood cell disorders, Hematological disorder, Renal failure.

How Olkem Trio Products work

Olmesartan Medoxomil + Cilnidipine + Chlorthalidone is a combination of three medicines: Olmesartan Medoxomil + Cilnidipine + Chlorthalidone1, Olmesartan Medoxomil + Cilnidipine + Chlorthalidone2 and Olmesartan Medoxomil + Cilnidipine + Chlorthalidone3. Olmesartan Medoxomil + Cilnidipine + Chlorthalidone1 is an angiotensin receptor blocker (ARB) and Olmesartan Medoxomil + Cilnidipine + Chlorthalidone2 is a calcium channel blocker (CCB). They work by widening and relaxing the blood vessels, thereby lowering blood pressure. Olmesartan Medoxomil + Cilnidipine + Chlorthalidone3 is a diuretic which removes extra water and certain electrolytes from the body through urine. Over time it also works by relaxing blood vessels and improving blood flow.

In Depth Information for Olkem Trio Products

You have been prescribed Olkem Trio for the treatment of high blood pressure.
Lowering high blood pressure helps prevent strokes and heart attacks.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Olkem Trio may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
Use of Olkem Trio during pregnancy or breastfeeding is unsafe.

Patient Concerns about Olkem Trio Products

Frequently asked questions about Olkem Trio Products

Q. What is Olkem Trio 12.5 Tablet used for?

Olkem Trio 12.5 Tablet is used to treat high blood pressure (hypertension). It helps relax blood vessels, reduce extra water in the body, and improve blood flow. All this together helps lower blood pressure effectively.

Q. When should I avoid taking Olkem Trio 12.5 Tablet?

You should avoid taking Olkem Trio 12.5 Tablet if you are pregnant or planning pregnancy, have severe kidney or liver disease, had a recent heart attack or suffer from serious heart failure, have a condition where you stop producing urine (anuria), have low levels of potassium or sodium, or high calcium or uric acid (like in gout) and/or are allergic to any ingredient in the Olkem Trio 12.5 Tablet.

Q. What are the common side effects of Olkem Trio 12.5 Tablet?

Some people may experience dizziness, swelling in the legs, tiredness, or increased urination. If any side effects bother you or worsen, consult your doctor.

Q. What are the most serious side effects of Olkem Trio 12.5 Tablet?

You should stop using Olkem Trio 12.5 Tablet and seek medical help if you notice serious side effects such as severe dizziness or fainting, muscle cramps or irregular heartbeat (can be due to low potassium), yellowing of eyes or skin (signs of liver trouble), sudden weight gain or swelling (signs of kidney issues), skin rash, itching, or trouble breathing (possible allergic reaction), etc.

Q. Can I stop taking Olkem Trio 12.5 Tablet if I feel better?

No. You should never stop taking Olkem Trio 12.5 Tablet without consulting your doctor. High blood pressure often has no symptoms, and stopping the medicine suddenly may cause complications.

Q. Can I take Olkem Trio 12.5 Tablet if I have kidney or liver problems?

Taking Olkem Trio 12.5 Tablet in severe liver or kidney issues may cause harm. If you have kidney or liver issues, talk to your doctor before taking Olkem Trio 12.5 Tablet. Your doctor may adjust the dose or suggest alternative medicine based on your condition.

Q. Does Olkem Trio 12.5 Tablet cause frequent urination?

Yes, one ingredient in Olkem Trio 12.5 Tablet, chlorthalidone, is a water pill (diuretic), which increases urine output. You may urinate more often, especially after the first few doses.

Q. Can Olkem Trio 12.5 Tablet affect blood sugar or cholesterol?

Yes, Olkem Trio 12.5 Tablet may increase blood sugar, uric acid, or cholesterol levels. If you have diabetes or gout, your doctor will monitor you more closely.

Q. Can Olkem Trio 12.5 Tablet make me feel dizzy or weak?

Yes, Olkem Trio 12.5 Tablet may cause dizziness, especially when standing up too quickly. It’s best to stand slowly and avoid driving or using machines until you know how the medicine affects you.

Q. When does Olkem Trio 12.5 Tablet start to show results?

The exact time Olkem Trio 12.5 Tablet takes to show results is not known. However, you may expect a control in your blood pressure in a few days of regular prescribed use. The full benefits may take a bit longer depending on the severity of your condition.

Q. Are there any foods or medicines I should avoid while taking Olkem Trio 12.5 Tablet?

While on Olkem Trio 12.5 Tablet treatment, you should avoid taking salt substitutes high in potassium, grapefruit juice (it may increase side effects), and other blood pressure medicines or diuretics without your doctor’s advice. Also tell your doctor if you take medicines for heart problems, diabetes, gout, or anti-inflammatory drugs like ibuprofen.

Information last updated by Dr. Varun Gupta, MD Pharmacology on 25th Nov 2025.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.