Test Detail
Understanding the Test
Test Measures
Interpreting Results
Other Tests
Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Viral Marker Profile

Viral Marker Profile Test Includes 3 testsView All
You need to provide
Blood
This test is for
Male, Female

Understanding Viral Marker Profile


What is Viral Marker Profile?

Viral Hepatitis and HIV have been recognized as a serious public health problem in India by the World Health Organisation (WHO). Viral Hepatitis is caused by Hepatitis virus A to E with Hepatitis A,B and C constituting the majority of cases. The cases of viral hepatitis and HIV infection are increasing due to intravenous drug abuse, sharing of needles and unsafe sex. A more serious concern is that most people infected with the virus are unaware of it. Therefore, we have come up with a unique one of its kind package which will screen you against the three most common types of Hepatitis Viruses i.e. A, B and C along with HIV package. So, get yourself tested today before its too late. Remember, Prevention is always better than cure.

What is Viral Marker Profile used for?

  1. If you have signs or symptoms suggesting acute hepatitis like jaundice, loss of appetite, nausea, vomiting, abdominal pain, fever or dark urine which might be due to Hepatitis B infection 
  2. If you have signs or symptoms of chronic hepatitis which might indicate hepatitis C infection 
  3. If you are pregnant 
  4. If  you have been in close contact with someone infected with Hepatitis B, C or HIV 
  5. If your health care practitioner is suspecting HIV infection 
  6. If you are on long term dialysis 
  7. If you have ever injected illegal drugs 



What does Viral Marker Profile measure?

Contains 3 tests
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HIV Combo (Antigen And Antibody) Test

An HIV Combo (Antigen And Antibody) Test simultaneously detects HIV p24 antigen and antibodies associated with HIV 1 & 2. The HIV p24 antigen is the most abundant HIV protein and its detection is used clinically to diagnose an HIV infection early on since HIV-specific antibodies are not detectable in a very recently acquired infection. HIV-1 was discovered first and is the most widespread, whereas HIV-2 is more than 55% genetically different from HIV-1. The transmission rate of HIV-2 is also slower than HIV-1. This test also helps to differentiate between the two HIV infections.

Know more about HIV Combo (Antigen And Antibody) Test

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HCV Antibody - Immunochromatography

An HCV Antibody - Immunochromatography test determines if HCV has infected you and helps your doctor guide your treatment. HCV causes liver inflammation and is classified into acute hepatitis infection and chronic hepatitis infection.

  • Acute hepatitis C: This occurs in the first six months after exposure to the hepatitis C virus. In the early stage of the infection, acute hepatitis C is mild and may cause no symptoms. For this reason, most people do not know they have this infection.

  • Chronic hepatitis C: If your body cannot fight off the virus, you can develop a chronic hepatitis C infection. Progression from acute to chronic hepatitis C is common, occurring in 75-85% of patients. Detecting chronic hepatitis C early is important to prevent future complications, such as liver failure, and initiate effective treatment.

Know more about HCV Antibody - Immunochromatography

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HBsAg Screening - Rapid

An HBsAg Screening - Rapid test confirms the presence of hepatitis B virus (HBV) in a suspected individual. HBsAg is the first serological marker, within 1 to 10 weeks, to appear in the blood after recent exposure to HBV. Persistence of this marker for more than 6 months implies chronic (long-term) HBV infection which may lead to liver damage (scarring or cirrhosis). A person who has a chronic infection is capable of spreading the infection to healthy individuals, even if they do not show or experience any symptoms.

Know more about HBsAg Screening - Rapid

Interpreting Viral Marker Profile results


Interpretations

  • A negative HCV antibody test indicates no infection with hepatitis C virus while positive or indeterminate HCV antibody test with negative HCV RNA signifies past infection. If both HCV antibody and HCV RNA are positive, it indicates current infection with Hepatitis C virus 
  • A negative test for HIV antigen or antibody usually indicates no infection with HIV virus while if both screening and confirmatory tests are positive, it usually signifies HIV infection 
  • A positive Hepatitis B surface antigen (HBsAg) and a positive Hepatitis B envelope antigen (HBeAg) indicates active infection with the virus 



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