Pulmocore Panel 2 near me in Mumbai
Understanding Pulmocore Panel 2 in Mumbai
What is Pulmocore Panel 2 in Mumbai?
pulmoCORE Panel 2 (EGFR (RT PCR), ALK (FISH), ROS-1 (FISH)) is a set of tests that detects genetic changes (mutations) in two different genes namely epidermal growth factor receptor (EGFR) gene and ROS-1 (Repressor of Silencing 1) gene. This panel also identifies anaplastic lymphoma kinase (ALK) gene rearrangement on chromosome 2. Any mutations in EGFR and ROS-1 genes can lead to non-small cell lung carcinoma (NSCLC), the most common form of lung cancer. Gene rearrangements involving the ALK gene are present in approximately 2-7% of non-small cell carcinomas of the lung (primarily adenocarcinomas). This panel provides important information that can guide treatment decisions in NSCLC patients and helps in identifying patients who may benefit from treatment with medicines including Crizotininb, Ceritinib, and Alectinib.
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