Test Detail
Overview

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Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Hemophilia A (Factor VIII) Inversions

You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation required

Overview


What is Hemophilia A (Factor VIII) Inversions?

The deficiency of clotting factor VIII is the main cause of the condition Hemophilia A. It is a rare condition that affects only about 0.02% of males. The major symptom in males is excessive bleeding. Females do not experience bleeding but are at a risk of delivering affected offspring. The test detects intron 22 inversion with F8 gene.


Why is Hemophilia A (Factor VIII) Inversions done?

This test is ideal for males affected with severe hemophIlia, who have been previously identified with a familial intron 22 inversion. The test is useful for first tier molecular testing. Women with a family history of severe haemophilia A must also get tested.


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