How can we help?

Home

G6PD Quantitative Reflex Qualitative

Also referred as

Glucose-6-Phosphate Dehydrogenase Test

Quantitative G6PD Test

157+ booked recently

For men & women

Earliest reports in

48 hours

Contains

3 tests

Know more about this test

The G6PD Quantitative Reflex Qualitative is a blood test that helps measure the activity of the enzyme glucose-6-phosphate dehydrogenase (G6PD) in red blood cells. G6PD deficiency is a genetic disorder that can cause hemolytic anemia, particularly in response to specific triggers like medications, foods, or infections.

Samples required

Blood

Find out

Why is this test booked?

Preparations

No special preparation is required.

Sample Collection

Who will collect your samples?

Understanding G6PD Quantitative Reflex Qualitative

G6PD is a crucial enzyme that protects red blood cells from oxidative damage by maintaining the stability of cellular membranes. A deficiency in this enzyme can lead to hemolytic anemia. In this condition, red blood cells break down faster than the body can produce them. This is especially common in response to certain triggers, such as infections, specific medications, or the consumption of fava beans (a condition known as "favism").

Early detection of G6PD deficiency allows individuals to avoid known triggers, thereby preventing hemolytic episodes. It is noteworthy that a quantitative analysis is performed to determine the actual concentration of G6PD enzyme activity in the blood. If the quantitative value is below 7.29 units/gm of Hb (hemoglobin), a reflex qualitative test is performed to confirm if the deficiency is significant.

The G6PD Quantitative Reflex Qualitative test is recommended in various scenarios. These include newborn screening, a family history of G6PD deficiency, and symptoms suggestive of hemolytic anemia, such as fatigue, jaundice, dark urine, and shortness of breath. It is especially advised for individuals from high-risk populations, such as males, African-American individuals, or those with a family history of G6PD deficiency. It is advised before exposure to triggering agents like certain medications (antibiotics, antimalarials, or sulfa drugs), pre-surgical screening, and investigation of anemia. It is also recommended for individuals traveling to malaria-endemic areas before taking antimalarials.

No special preparation is required for this test. However, inform the doctor about all the medications or supplements being taken, as these may affect the test results, potentially requiring adjustments or temporary discontinuation. Narrate the complete medical history to help doctors relate the clinical and laboratory findings.

Lab test results may vary across laboratories. Do not self-medicate. Always consult the doctor to understand the test results correctly. The insights from G6PD Quantitative Reflex Qualitative test will help doctors formulate the overall treatment plan.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

What does G6PD Quantitative Reflex Qualitative measure?

Contains 3 tests

The G6PD Quantitative Reflex Qualitative test measures the concentration of the G6PD enzyme in red blood cells, an essential enzyme that plays a critical role in preventing RBCs from oxidative stress by helping regenerate glutathione, a molecule that neutralizes harmful oxidative substances. When there is a deficiency in G6PD, red blood cells become more susceptible to oxidative damage from certain triggers such as infections, medications (e.g., antibiotics, antimalarials), or specific foods (like fava beans).

This test identifies whether an individual has G6PD deficiency, which is crucial in managing conditions associated with oxidative stress. If G6PD enzyme activity is found to be low or absent, it helps explain the cause of recurring hemolytic episodes, jaundice (yellowing of the skin and eyes), and other related symptoms. This quantitative measurement helps doctors understand the extent of enzyme deficiency and determine the most appropriate interventions to prevent future episodes.

Hb (Hemoglobin)

An Hb (Hemoglobin) test measures the concentration of hemoglobin protein in your blood. Hemoglobin is made up of iron and globulin proteins. It is an essential part of RBCs and is critical for oxygen transfer from the lungs to all body tissues. Most blood cells, including RBCs, are produced regularly in your bone marrow. The Hb test is a fundamental part of a complete blood count (CBC) and is used to monitor blood health, diagnose various blood disorders, and assess your response to treatments if needed.

Know more about Hb (Hemoglobin)

G6PD Test By Kinetic Method

G6PD-Quantitative, Blood By Kinetic Method

Frequently booked together

FAQs related to G6PD Quantitative Reflex Qualitative

What is the G6PD Quantitative Reflex Qualitative test?

The G6PD Quantitative Reflex Qualitative test measures the concentration of glucose-6-phosphate dehydrogenase (G6PD) enzyme in the blood. If the enzyme levels are found to be low, a reflex qualitative test is conducted to confirm a deficiency.

Why do I need the G6PD Quantitative Reflex Qualitative test?

You may need this test if you have symptoms of hemolytic anemia, such as fatigue, jaundice, and dark urine, or if you've experienced episodes of anemia after taking certain medications, eating fava beans, or following an infection. It may also be recommended if there is a family history of G6PD deficiency.

How is the G6PD Quantitative Reflex Qualitative test different from the standard G6PD Qualitative test?

The quantitative reflex test provides an exact measurement of G6PD enzyme levels, whereas the standard qualitative test only indicates whether enzyme activity is normal or deficient. The reflex test offers more precise results, especially in borderline or unclear cases.

What do the test results mean?

A normal G6PD enzyme level indicates no deficiency. While a low G6PD enzyme level with reflex confirmation suggests G6PD deficiency, indicating a higher risk of hemolysis under specific triggers.

Do I need to fast before taking the test?

No, fasting is not required for the G6PD Quantitative Reflex Qualitative test. You can take the test at any time of the day.

How is the test performed?

The test involves a simple blood draw, typically from a vein in your arm. The sample is then analyzed in a laboratory to measure the concentration of the G6PD enzyme activity in your red blood cells.

Are there any risks associated with the test?

No, the G6PD Quantitative Reflex Qualitative test is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection, but chances of serious complications are extremely rare.

Can this test be used for newborn screening?

While the qualitative test is commonly used for newborn screening, the quantitative reflex test may be used in specific cases where more detailed information is needed, especially if initial screening results are borderline or unclear.

Is there any cure for G6PD deficiency?

There is no cure for G6PD deficiency, but it can be managed effectively by avoiding known triggers, such as certain medications, foods (like fava beans), and infections that can induce hemolysis.

How often should this test be done?

The frequency of this test depends on the individual's medical history and the doctor's recommendation. If you have been diagnosed with G6PD deficiency, your doctor may recommend regular testing to monitor your condition.

Can the G6PD Quantitative Reflex Qualitative test be done at home?

Yes, you can take the G6PD Quantitative Reflex Qualitative test from the comfort of your home with Tata 1mg labs.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

Content created by

Dr. Swati Gupta (Anand)

MD Lab Medicine, MBBS

Want to know moreRead our editorial policy

Last Updated

17th Oct 2025