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G6PD - Quantitative Reflex Qualitative

Also referred as
Glucose-6-Phosphate Dehydrogenase Test
Quantitative G6PD Test
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3 tests
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₹809
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The G6PD - Quantitative Reflex Qualitative is a blood test that helps measure the activity of the enzyme glucose-6-phosphate dehydrogenase (G6PD) in red blood cells. G6PD deficiency is a genetic disorder that can cause hemolytic anemia, particularly in response to specific triggers like medications, foods, or infections. 

Samples required
Blood
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Preparations
No special preparation is required.
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This is an outsourced test. The sample for this test is collected by Tata 1mg and processed at a NABL-accredited partner lab.
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Understanding G6PD - Quantitative Reflex Qualitative

G6PD is a crucial enzyme that protects red blood cells from oxidative damage by maintaining the stability of cellular membranes. A deficiency in this enzyme can lead to hemolytic anemia. In this condition, red blood cells break down faster than the body can produce them. This is especially common in response to certain triggers, such as infections, specific medications, or the consumption of fava beans (a condition known as "favism").

Early detection of G6PD deficiency allows individuals to avoid known triggers, thereby preventing hemolytic episodes. It is noteworthy that a quantitative analysis is performed to determine the actual concentration of G6PD enzyme activity in the blood. If the quantitative value is below 7.29 units/gm of Hb (hemoglobin), a reflex qualitative test is performed to confirm if the deficiency is significant.

The G6PD - Quantitative Reflex Qualitative test is recommended in various scenarios. These include newborn screening, a family history of G6PD deficiency, and symptoms suggestive of hemolytic anemia, such as fatigue, jaundice, dark urine, and shortness of breath. It is especially advised for individuals from high-risk populations, such as males, African-American individuals, or those with a family history of G6PD deficiency. It is advised before exposure to triggering agents like certain medications (antibiotics, antimalarials, or sulfa drugs), pre-surgical screening, and investigation of anemia. It is also recommended for individuals traveling to malaria-endemic areas before taking antimalarials.

No special preparation is required for this test. However, inform the doctor about all the medications or supplements being taken, as these may affect the test results, potentially requiring adjustments or temporary discontinuation. Narrate the complete medical history to help doctors relate the clinical and laboratory findings.

Lab test results may vary across laboratories. Do not self-medicate. Always consult the doctor to understand the test results correctly. The insights from G6PD - Quantitative Reflex Qualitative test will help doctors formulate the overall treatment plan.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does G6PD - Quantitative Reflex Qualitative measure?

Contains 3 tests

The G6PD - Quantitative Reflex Qualitative test measures the concentration of the G6PD enzyme in red blood cells, an essential enzyme that plays a critical role in preventing RBCs from oxidative stress by helping regenerate glutathione, a molecule that neutralizes harmful oxidative substances. When there is a deficiency in G6PD, red blood cells become more susceptible to oxidative damage from certain triggers such as infections, medications (e.g., antibiotics, antimalarials), or specific foods (like fava beans). 

This test identifies whether an individual has G6PD deficiency, which is crucial in managing conditions associated with oxidative stress. If G6PD enzyme activity is found to be low or absent, it helps explain the cause of recurring hemolytic episodes, jaundice (yellowing of the skin and eyes), and other related symptoms. This quantitative measurement helps doctors understand the extent of enzyme deficiency and determine the most appropriate interventions to prevent future episodes.

The Hb (Hemoglobin) test measures the concentration of hemoglobin in your blood. Hemoglobin binds oxygen molecules and carries them to body tissues while removing carbon dioxide. Low hemoglobin suggests reduced oxygen-carrying capacity. It can be due to anemia, bleeding, nutritional deficiencies (iron, vitamin B12, folate), or chronic disease. High hemoglobin may occur in dehydration, living at high altitudes, smoking, or diseases like polycythemia vera.

Know more about Hb (Hemoglobin)

G6PD Test By Kinetic Method
G6PD-Quantitative, Blood By Kinetic Method
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G6PD - Quantitative Reflex Qualitative test price for other cities

Price inMumbaiRs. 1079
Price inBangaloreRs. 1089
Price inKolkataRs. 1089
Price inThaneRs. 1079
Price inPuneRs. 1089
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FAQs related to G6PD - Quantitative Reflex Qualitative

The G6PD - Quantitative Reflex Qualitative test measures the concentration of glucose-6-phosphate dehydrogenase (G6PD) enzyme in the blood. If the enzyme levels are found to be low, a reflex qualitative test is conducted to confirm a deficiency.
You may need this test if you have symptoms of hemolytic anemia, such as fatigue, jaundice, and dark urine, or if you've experienced episodes of anemia after taking certain medications, eating fava beans, or following an infection. It may also be recommended if there is a family history of G6PD deficiency.
The quantitative reflex test provides an exact measurement of G6PD enzyme levels, whereas the standard qualitative test only indicates whether enzyme activity is normal or deficient. The reflex test offers more precise results, especially in borderline or unclear cases.
A normal G6PD enzyme level indicates no deficiency. While a low G6PD enzyme level with reflex confirmation suggests G6PD deficiency, indicating a higher risk of hemolysis under specific triggers.
No, fasting is not required for the G6PD - Quantitative Reflex Qualitative test. You can take the test at any time of the day.
The test involves a simple blood draw, typically from a vein in your arm. The sample is then analyzed in a laboratory to measure the concentration of the G6PD enzyme activity in your red blood cells.
No, the G6PD - Quantitative Reflex Qualitative test is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection, but chances of serious complications are extremely rare.
While the qualitative test is commonly used for newborn screening, the quantitative reflex test may be used in specific cases where more detailed information is needed, especially if initial screening results are borderline or unclear.
There is no cure for G6PD deficiency, but it can be managed effectively by avoiding known triggers, such as certain medications, foods (like fava beans), and infections that can induce hemolysis.
The frequency of this test depends on the individual's medical history and the doctor's recommendation. If you have been diagnosed with G6PD deficiency, your doctor may recommend regular testing to monitor your condition.
Yes, you can take the G6PD - Quantitative Reflex Qualitative test from the comfort of your home with Tata 1mg labs.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
Recommended for everyone
This package is designed with everyone’s overall health considerations in mind, offering assessments to address a wide range of wellness needs.
Package can be booked by :
Men
Women
Contains 3 tests
Hb (Hemoglobin)
G6PD Test By Kinetic Method
G6PD-Quantitative, Blood By Kinetic Method
Report delivery
Standard time
72 hrs
For slots after 11 AM, report will be delivered in 72 hours.
Samples required
Blood
Our phlebotomist will draw a blood sample, typically from a vein in your inner elbow.
Preparations
1
No special preparation is required.
Why is this test booked?
1
To diagnose G6PD deficiency, especially in individuals with unexplained hemolytic anemia.
2
To evaluate if hemolytic anemia is due to G-6-PD deficiency, especially after exposure to certain drugs, infections, or foods (e.g., fava beans).
3
To help identify the cause of neonatal jaundice.
4
To monitor individuals from high-risk ethnic backgrounds who may be at risk of hemolytic episodes.
5
To assess G6PD enzyme activity before administering medications that may trigger hemolysis.
6
To assess the effectiveness of treatments for conditions related to G-6-PD deficiency, such as during or after a hemolytic episode.
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