ETV6-NTRK 3 translocation by RT PCR near me in Kolkata

The ETV6-NTRK 3 translocation by RT PCR test is used to detect the ETV6-NTRK3 gene fusion, which results from a chromosomal translocation between the ETV6 gene on chromosome 12 and the NTRK3 gene on chromosome 15. This fusion is associated with certain cancers, including infantile fibrosarcoma, secretory breast carcinoma, and congenital mesoblastic nephroma. The test uses RT-PCR (Reverse Transcriptase Polymerase Chain Reaction) to identify the presence of this specific gene fusion. Detecting this fusion helps confirm the diagnosis and may also guide treatment, as NTRK gene fusions can be targeted with specific therapies. This test is especially useful when the tumor shows histological features suggestive of an NTRK-related cancer.

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