Double Marker Test- First Trimester near me in Varanasi
Understanding Double Marker Test- First Trimester in Varanasi
What is Double Marker Test- First Trimester in Varanasi?
A Double Marker Test- First Trimester is a prenatal screening test typically conducted between the 11th and 13th week i.e., the first trimester of pregnancy, and tells about the risk of specific chromosomal abnormalities, such as Down syndrome( Trisomy 21), Edwards’s syndrome (Trisomy 18) and Trisomy 13 in the developing fetus. This test is available at an affordable price in Varanasi with Tata 1mg labs.
This test measures the levels of two biomarkers in the mother’s blood: human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). The levels of these markers, along with maternal age, gestational age, and ultrasound findings help determine the likelihood of chromosomal abnormalities in the fetus. These abnormalities can lead to various genetic conditions that can affect the baby’s growth and development. Therefore, their early detection is vital for ensuring comprehensive prenatal care and addressing potential health challenges effectively. No special preparation is required for this test.
What does Double Marker Test- First Trimester measure?
The test is named “Double Marker” or “Dual Marker” as it primarily focuses on two biomarkers associated with chromosomal abnormalities: free beta-hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein-A). These, along with the USG marker and nuchal translucency (NT) measurement, are effective in Combined screening for Down syndrome and trisomy 13/18 in the fetus. This test only gives the risk for the presence of these chromosomal abnormalities in the developing fetus. A positive screen is not diagnostic but indicates that further evaluation should be considered.
hCG is synthesized by the placenta very early in pregnancy and can be detected in the blood 8-11 days after conception. Higher than normal levels of this hormone after 11 weeks of gestation indicate an increased risk for Down syndrome, while low levels indicate an increased risk for trisomy 18.
PAPP-A is a protein produced by the placenta that is needed for the implantation and maintenance of a healthy placenta (afterbirth). Low levels of PAPP-A before the 14th week of pregnancy suggest an increased risk of fetal chromosomal abnormalities.