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Autoimmune Liver Diseases IgG Profile, LIA

Autoimmune Liver Diseases IgG Profile, LIA near me in Rajkot

Also referred as
Autoimmune Liver Disease Profile
For men & women
Earliest reports in
72 hours
Contains
6 tests
Know more about this test

The Autoimmune Liver Diseases IgG Profile, LIA is a group of blood tests that helps detect several key markers associated with autoimmune liver conditions such as autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC). These conditions occur when the immune system mistakenly attacks healthy liver cells (producing autoantibodies), leading to inflammation and potential liver damage. This profile is widely available with Tata 1mg labs at an affordable price in Rajkot.

The profile involves qualitative measurement of IgG class antibodies against AMA M2, Sp100, LKM1, gp210, LC1 and SLA (antigens) using the line immunoassay (LIA) technique. Early detection and treatment are important to manage these conditions and prevent serious liver damage such as cirrhosis and liver failure.

Doctors may recommend this profile if there are symptoms such as ongoing fatigue, yellowing of the skin or eyes (jaundice), itching, abdominal discomfort, or abnormal liver function test results. The profile is also done to check how well the treatment effectiveness or disease progression over the time. Additionally, it can  help rule out other liver problems that have similar signs and symptoms such as viral hepatitis, fatty liver disease, or drug-induced liver injury.

No special preparation is required for this test. Eat and drink as per the daily routine.

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Blood
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Understanding Autoimmune Liver Diseases IgG Profile, LIA

The Autoimmune Liver Diseases IgG Profile, LIA checks for specific IgG autoantibodies (proteins)  linked to autoimmune liver diseases. This profile helps find out if someone has conditions like autoimmune hepatitis (AIH) or primary biliary cholangitis (PBC). It can also help distinguish between liver conditions so that the right treatment can be initiated. It can also help distinguish between different liver conditions and rule out other problems with similar symptoms such as viral hepatitis, fatty liver disease, or drug-induced liver injury.

The profile helps detect the presence of IgG antibodies against antigens such as AMA M2, Sp100, LKM1, gp210, LC1 and SLA, using the line immunoassay (LIA) technique. Early detection and treatment are important to manage these conditions and prevent serious liver damage such as cirrhosis and liver failure.

Doctors may recommend this profile if there are symptoms such as ongoing fatigue, yellowing of the skin or eyes (jaundice), itching, abdominal discomfort, or abnormal liver function test results. The profile is also done to assess the effectiveness of the treatment or the progression of the disease over time. 

No special preparation is required for the Autoimmune Liver Diseases IgG Profile, LIA. It is important to inform the doctor about all the medicines and supplements being taken, as these may affect the test results potentially requiring dosage adjustments or temporary discontinuation before the test. 

Test result ranges may vary across laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor an appropriate treatment plan.

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What does Autoimmune Liver Diseases IgG Profile, LIA measure?

Contains 6 tests

The Autoimmune Liver Diseases IgG Profile, LIA measures the presence of specific autoantibodies that attack components of the liver and associated cells, helping confirm a diagnosis of autoimmune liver disease. These antibodies include:

  • AMA M2: Indicates the presence of antimitochondrial antibodies, which are specific for primary biliary cholangitis (PBC).
  • Sp100: Indicates antibodies against the Sp100 protein, which are associated with PBC.
  • gp210: Indicates antibodies against the gp210 protein, which are associated with PBC.
  • LKM1: Indicates the presence of anti-liver kidney microsomal antibodies type 1, which are associated with autoimmune hepatitis type 2 (AIH-2).
  • LC1: Indicates the presence of antibodies against the LC1 protein, which are associated with AIH-2.
  • SLA: Indicates the presence of antibodies against the SLA protein, which are associated with AIH.

Together, these markers provide valuable insights for diagnosing and classifying autoimmune liver diseases, particularly when clinical signs overlap or mimic other liver conditions. 

AMA-M2 LIA
SP100
LKM1
GP210
LC1
SLA

FAQs related to Autoimmune Liver Diseases IgG Profile, LIA in Rajkot

It is a group of blood tests that checks for special IgG antibodies that may be attacking your liver by mistake. These antibodies help find out if you have an autoimmune liver problem.
You may need this test if you have symptoms like tiredness, stomach pain, yellow eyes or skin (jaundice), or itchy skin. It helps doctors find the exact cause of your liver problem.
It can help detect autoimmune liver diseases like autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC).
This test checks for several IgG antibodies, including AMA-M2 LIA, SP100, LKM1, GP210, LC1, and SLA.
No, you don’t need to fast. You can eat and drink normally unless your doctor tells you otherwise.
A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
No, the Autoimmune Liver Diseases IgG Profile, LIA is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection but chances of serious complications are extremely rare.
Yes. In Rajkot, you can schedule the Autoimmune Liver Diseases IgG Profile, LIA near you with Tata 1mg Labs. The profile is easy to book, cost-effective, and available with a comprehensive report.
Yes, the Autoimmune Liver Diseases IgG Profile, LIA is eligible for home sample collection in Rajkot. With Tata 1mg Labs, you can schedule a test at your convenience, and select a date and time for sample collection that fits your schedule.
If you want to schedule the Autoimmune Liver Diseases IgG Profile, LIA with Tata 1mg Labs in Rajkot, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want to the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Rajkot. The Autoimmune Liver Diseases IgG Profile, LIA is available at an affordable price of Rs. 5000.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 72 hours to provide the reports of the Autoimmune Liver Diseases IgG Profile, LIA in Rajkot.
Content created by
Written by:
Dr. Lipika Khurana
PGDHHM, BDS
Reviewed by:
Dr. Naziya Maner
DNB, DCP
Want to know moreRead our editorial policy
Last Updated11th Oct 2025

Autoimmune Liver Diseases IgG Profile, LIA test price for other cities

Price inBangaloreRs. 5000
Price inMumbaiRs. 5000
Price inRanchiRs. 5000
Price inNoidaRs. 5000
Price inFaridabadRs. 5000

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References

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    Mercado LA, Gil-Lopez F, Chirila RM, Harnois DM. Autoimmune Hepatitis: A Diagnostic and Therapeutic Overview. Diagnostics (Basel). 2024 Feb 9;14(4):382. [Accessed 30 Jun. 2025].
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Tata 1mg certified phlebotomists
Contains 6 tests
AMA-M2 LIA
SP100
LKM1
GP210
LC1
SLA