
VZV (Varicella Zoster Virus) DNA Detection by RT-PCR









The VZV (Varicella Zoster Virus) DNA Detection by RT-PCR test is used to detect the presence of varicella zoster virus (VZV) DNA in blood samples. This virus is responsible for causing chickenpox (primary infection) and shingles (reactivation). This test supports timely diagnosis, which helps guide treatment.












Understanding VZV (Varicella Zoster Virus) DNA Detection by RT-PCR
Varicella zoster virus (VZV) is a highly contagious herpesvirus that causes two major conditions: chickenpox (usually in children) and shingles (in adults due to reactivation of latent virus). After initial infection, the virus remains dormant in nerve tissues and can reactivate later in life, leading to painful rashes and other neurological complications.
The VZV (Varicella Zoster Virus) DNA Detection by RT-PCR test identifies VZV genetic material in a blood sample. It helps confirm an active or reactivated infection, especially in cases where symptoms are not clearly visible or when complications are suspected. This test is particularly useful for detecting VZV in individuals at high risk, such as those with weakened immunity or neurological symptoms linked to viral reactivation.
This test is advised if there are symptoms such as fever, fatigue, headache, itchy blister-like rash on the skin, etc., suggestive of recent VZV infections or exposure to the virus. It is primarily used to support the diagnosis of primary varicella (chickenpox) or to help differentiate between primary infection and reactivation of the virus (shingles) when combined with other findings. It is also useful in evaluating VZV-related complications such as encephalitis, meningitis, or disseminated infections. This test is especially important in hospitalized or immunocompromised patients, where timely diagnosis can guide immediate antiviral treatment and help prevent serious complications or spread to others.
No special preparation is required for this test. However, it is important to inform the doctor about any recent illnesses, vaccinations, or medications, as these factors may impact the results.
Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly.
Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.
What does VZV (Varicella Zoster Virus) DNA Detection by RT-PCR measure?
The VZV (Varicella Zoster Virus) DNA Detection by RT-PCR measures the presence of varicella zoster virus (VZV) DNA in the blood sample. This test uses Real-Time Polymerase Chain Reaction (RT-PCR) technology, which amplifies and detects even tiny amounts of VZV DNA with high accuracy and speed. By identifying the genetic material of the virus directly, it supports the diagnosis of active infection; interpretation depends on symptoms and sample type, even when symptoms are unclear or when early diagnosis is critical (such as in immunocompromised patients or those with neurological symptoms).
A positive result indicates the presence of VZV in the body, suggesting infection. A negative result usually rules out active viral presence at the time of testing, although clinical correlation is always essential for final diagnosis.





FAQs related to VZV (Varicella Zoster Virus) DNA Detection by RT-PCR
- Laboratory Testing for Varicella-Zoster Virus (VZV) [Internet]. CDC; 31 Oct. 2019 [Accessed 05 Aug. 2024]. Available from:
- Vossen MT, Gent MR, Peters KM, Wertheim-van Dillen PM, Dolman KM, van Breda A, van Lier RA, Kuijpers TW. Persistent detection of varicella-zoster virus DNA in a previously healthy child after severe chickenpox. J Clin Microbiol. 2005 Nov;43(11):5614-21. [Accessed 05 Aug. 2025]. Available from:
- Saleh HM, Kumar S. Varicella-Zoster Virus (Chickenpox) [Updated 2025 Apr 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from:
Other tests
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)





