52 gene Focused Cancer NGS panel (DNA +RNA) - Mutation, Fusion & Copy Number Alterations near me in Pune

The 52 gene Focused Cancer NGS panel (DNA +RNA) - Mutation, Fusion & Copy Number Alterations test is an advanced genetic test is used to analyze cancer-related changes in 52 key genes using Next-Generation Sequencing (NGS). It examines tumor DNA and RNA extracted from a tissue sample (FFPE block) to detect three types of genetic alterations: mutations, gene fusions, and copy number variants (CNVs).

In this case of non-small cell lung cancer, the tumor showed approximately 60–65% neoplastic (cancer) cells. The NGS panel identified the following findings:

1. EGFR exon 19 deletion mutation – a known Tier 1A pathogenic mutation associated with treatment response to targeted therapies.

2. PIK3CA and CTNNB1 missense mutations, both of which may have clinical relevance.

3. No significant gene fusions or CNVs were detected.

This test plays a crucial role in precision oncology, helping guide personalized treatment decisions based on the genetic profile of the tumor.

Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.