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Zileuton is used to prevent asthma.

How it works

Zileuton belongs to a class of medications called leukotriene synthesis inhibitors. It works by blocking the formation of a substance called leukotriene, which helps to decrease certain asthma and allergy symptoms.

Common side effects

Nasal irritation, Abdominal pain, Diarrhoea, Facial pain, Face fullness, Headache, Heartburn, Muscle pain


No medicine available

Expert advice

  • You should take the extended-release tablet within one hour after the morning and evening meals.
  • Do not use Zileuton to treat a sudden asthma attack. Always carry a short-acting inhaler prescribed by your doctor to treat sudden asthma attack.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Zileuton may cause drowsiness/dizziness.Do not drive or operate machinery until you feel fine.
  • Zileuton may change your mental health in unexpected ways. Tell your doctor if you experience any mental or mood changes, including sleep problems and behavior changes. Your doctor will decide if you should continue taking Zileuton.
  • Do not consume alcohol while taking Zileuton treatment, as it may worsen the side effects.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)