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Vildagliptin is used to control blood sugar levels in patients with type 2 diabetes mellitus.

How it works

Vildagliptin belongs to class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. Vidagliptin works by making the pancreas produce more insulin and less glucagon. This helps to control the blood sugar level. This medicine has been shown to reduce blood sugar, which may help to prevent complications of diabetes.

Common side effects

Constipation, Cough, Dizziness, Headache, Increased sweating, Nasopharyngitis


Expert advice

Do not take this medication and consult your doctor if:
  • You have type 1 diabetes or if you have serious complication of diabetes where high levels of blood acids called ketones are produced in your body (diabetic ketoacidosis).
  • You are taking other antidiabetic drug known as a sulphonylurea, may cause low blood glucose (hypoglycemia).
  • You have moderate or severe kidney disease, liver disease, heart failure.
  • You are on dialysis.
  • You have or have had a disease of the pancreas.
Avoid driving or operating heavy machines if you feel dizzy.

Frequently asked questions


Q. Is vildagliptin safe?
Vildagliptin (also available as galvus, jalra) is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
 Q. How is vildagliptin metabolized?
Vildagliptin is metabolized by the process of hydrolysis in kidney.
Q. Does vildagliptin cause weight gain?
Body weight usually does not change with vildagliptin therapy. However, consult your doctor, if you experience weight gain.
Q. Is vildagliptin better than sitagliptin?
Vildagliptin and sitagliptin belong to same class of drugs and are equally effective and safe in treatment of type 2 diabetes mellitus. Always follow doctor’s advice regarding its use.
Q. Is vildagliptin licensed with insulin?
Vildagliptin can be taken in combination with insulin when prescribed by doctor. Always follow doctor’s advice regarding its use.

Content on this page was last updated on 18 October, 2016, by Dr. Varun Gupta (MD Pharmacology)