Information about Venetoclax

Venetoclax Uses

Venetoclax is used in the treatment of sickle cell anemia, blood cancer (chronic lymphocytic leukemia), prostate cancer, blood cancer (acute lymphocytic leukemia), soft tissue sarcoma and Hodgkin’s disease.

How Venetoclax works

Venetoclax is an antineoplastic agent that is used to treat certain blood cancers. It works by blocking a protein called B-cell lymphoma/leukemia 2 (BCL-2), which helps cancer cells live longer than they should. It turns off this protein and helps the cancer cells die naturally and be removed from the body.

Common side effects of Venetoclax

Decreased white blood cell count (neutrophils), Low blood platelets, Anemia (low number of red blood cells), Diarrhea, Nausea, Upper respiratory tract infection, Cough, Musculoskeletal (bone, muscle or joint) pain, Fatigue, Edema (swelling)
CONTENT DETAILS
Reviewed By
MD Pharmacology, MBBS
Written By
MMST, MBBS
Last updated
23 May 2025 | 07:19 PM (UTC)

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Available Medicine for Venetoclax

VenclextaAbbVie Therapeutics India Private Limited
2054 to ₹136942 variant(s)

Expert advice for Venetoclax

  • Regular blood tests are essential to monitor your blood cell counts and kidney function. This helps your doctor adjust your treatment if needed.
  • Keep Venetoclax in its original packaging, away from moisture and heat. Do not transfer them to another container.
  • Keep an updated list of all medicines, vitamins, and supplements you are taking, and share it with every doctor you visit.
  • Venetoclax can lower your body’s ability to fight infections. Report signs like fever, chills, or persistent sore throat promptly to your doctor.

Frequently asked questions for Venetoclax

Venetoclax

Q. How should I take Venetoclax?

Take Venetoclax exactly as prescribed by your doctor. It is usually started at a low dose and increased gradually. Always follow your dosing schedule and avoid missing doses.

Q. Are there any food or drug interactions?

Yes. Avoid grapefruit or Seville oranges, as they can affect how Venetoclax works. Also, tell your doctor about all other medicines you are taking to avoid possible interactions.

Q. Can I stop taking Venetoclax if I feel better?

No, do not stop or change your dose without talking to your doctor. Even if you feel better, it’s important to continue as prescribed to keep the cancer under control.

Q. Is Venetoclax safe during pregnancy or breastfeeding?

Venetoclax is not recommended during pregnancy or breastfeeding. Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

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