Valsartan + Hydrochlorothiazide

Information about Valsartan + Hydrochlorothiazide

Valsartan + Hydrochlorothiazide Uses

Valsartan+Hydrochlorothiazide is used in the treatment of Hypertension (high blood pressure).

How Valsartan + Hydrochlorothiazide works

Valsartan + Hydrochlorothiazide is a combination of two medicines: Valsartan and hydrochlorothiazide which lower blood pressure effectively. Valsartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Common side effects of Valsartan + Hydrochlorothiazide

Nausea, Taste change, Diarrhea, Upset stomach, Dizziness, Decreased blood pressure, Headache, Fatigue, Increased blood lipid level, Electrolyte imbalance, Increased blood uric acid, Glucose intolerance
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated:
26 Jun 2020 | 03:19 PM (UTC)
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Available Medicine for Valsartan + Hydrochlorothiazide

Valzaar-HTorrent Pharmaceuticals Ltd
135 to ₹2914 variant(s)
Valent-HLupin Ltd
1271 variant(s)
CO Diovan FctNovartis India Ltd
744 to ₹9302 variant(s)
Co-DiovanNovartis India Ltd
744 to ₹9302 variant(s)
Valembic HAlembic Pharmaceuticals Ltd
143 to ₹1602 variant(s)
Valfect HAstraZeneca
1041 variant(s)

Expert advice for Valsartan + Hydrochlorothiazide

  • You have been prescribed Valsartan + Hydrochlorothiazide for the treatment of high blood pressure.
  • It can be taken with or without food.
  • Valsartan + Hydrochlorothiazide may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position. 
  • Use of Valsartan + Hydrochlorothiazide during pregnancy or breastfeeding is unsafe.
  • It may also decrease the risk of stroke and heart attacks.

Frequently asked questions for Valsartan + Hydrochlorothiazide

Valsartan + Hydrochlorothiazide

Q. How long does it take for Valsartan+Hydrochlorothiazide to start working?

A substantial decrease in blood pressure can be experienced within 2 weeks of starting Valsartan+Hydrochlorothiazide. However, the medicine may take up to 4 weeks to show its complete effects. Talk to your doctor in case you have any concerns regarding Valsartan+Hydrochlorothiazide, but do not stop taking it without consulting the doctor.

Q. Which medicine is considered safe for treating high blood pressure?

There are many blood pressure-lowering medicines which can be considered safe. The doctor will advise the exact use of these medicines, keeping various factors such as age, gender, other coexisting diseases, etc. into consideration. Also, the effect of the medicine and response of the patient can vary from person to person. For instance, a person below 55 years of age having no other co-existing disease may be prescribed angiotensin II receptor antagonists (ARAs) (e.g., Valsartan+Hydrochlorothiazide, losartan, olmesartan) or Angiotensin Converting Enzyme (ACE) Inhibitors (e.g., ramipril, captopril or enalapril) by the doctor.

Q. Is Valsartan+Hydrochlorothiazide bad for kidneys?

Valsartan+Hydrochlorothiazide does not generally affect the working of a proper functioning kidney. However, there is limited data to support the safety of patients who have existing severe kidney impairment (creatinine clearance <10 ml/min) and are on dialysis. Hence, Valsartan+Hydrochlorothiazide should be used cautiously in such patients. It should only be used when advised by the doctor.

Q. Who should not be given Valsartan+Hydrochlorothiazide?

Valsartan+Hydrochlorothiazide should not be given to patients who are allergic to it, have severe liver disease, have diabetes or impaired kidney function. Also, its use should be restricted if you are being treated with blood pressure lowering medicine containing Aliskiren. In addition to that, Valsartan+Hydrochlorothiazide should not be used if you are pregnant or trying to conceive. If you are not sure or have any queries, consult your doctor.

Q. Does Valsartan+Hydrochlorothiazide cause weight gain?

No, Valsartan+Hydrochlorothiazide does not cause weight gain as a side effect. However, if your kidney function deteriorates, your body may swell due to the accumulation of water (fluid retention), resulting in weight gain. Inform your doctor if you experience any unexplained weight gain or swelling in your feet, ankles or hands.

Q. How long do I need to take Valsartan+Hydrochlorothiazide?

Continue taking Valsartan+Hydrochlorothiazide as long as your doctor has prescribed. Do not stop taking it even if you start feeling better. You may even have to take it lifelong, since Valsartan+Hydrochlorothiazide does not cure high blood pressure or heart failure but controls them.

Q. What is the most important information I should know about Valsartan+Hydrochlorothiazide?

Taking Valsartan+Hydrochlorothiazide during the last months of pregnancy can cause serious harm or even endanger the unborn baby. Therefore, do not take Valsartan+Hydrochlorothiazide if you are pregnant. Inform your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking Valsartan+Hydrochlorothiazide, stop taking Valsartan+Hydrochlorothiazide and call your doctor immediately.

Q. Can I switch in between the brands of Valsartan+Hydrochlorothiazide, since currently the brand I am using is not available?

No, do not switch to a different Valsartan+Hydrochlorothiazide product unless your doctor says that you should. Since you have to take it daily, keep a stock of it. Each Valsartan+Hydrochlorothiazide product releases the medication differently in your body and cannot be used interchangeably. Therefore, if you have any concerns regarding Valsartan+Hydrochlorothiazide, consult your doctor.


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