Information about Trimipramine

Trimipramine Uses

Trimipramine is used in the treatment of depression.

How Trimipramine works

Trimipramine is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Common side effects of Trimipramine

Increased heart rate, Weight gain, Dryness in mouth, Constipation, Difficulty in urination, Orthostatic hypotension (sudden lowering of blood pressure on standing)
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MD Pharmacology, MBBS
Last updated
12 Sep 2022 | 06:36 AM (UTC)

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Available Medicine for Trimipramine

Sizonorm PlusCrescent Therapeutics Ltd
101 variant(s)
7 to ₹162 variant(s)

Expert advice for Trimipramine

  • It may take 4 to 6 weeks for Trimipramine to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Trimipramine as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Frequently asked questions for Trimipramine


Q. What is Trimipramine used for?

Trimipramine belongs to a group of medicines known as antidepressants, used to treat depression. It works by restoring the chemical imbalance in the brain which helps to improve mood and behavior.

Q. What all should I inform my doctor before taking Trimipramine?

Before taking Trimipramine, you should tell your doctor if you are allergic to Trimipramine or any of its ingredients to avoid any allergic reactions. Inform your doctor if you have any problems with your heart, liver, thyroid, prostate or kidneys. Tell your doctor if you have or ever had epilepsy (seizures or fits), diabetes, or glaucoma. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Also, inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.

Q. Is Trimipramine effective?

Yes, Trimipramine is effective if taken in the dose and duration prescribed by the doctor. Avoid skipping doses and tell your doctor if you experience any side effects while taking Trimipramine. The doctor may suggest ways to manage or prevent them. It may take a few weeks for you to see improvement in your symptoms. However, the treatment may be continued for a few months for effective management of your condition.

Q. What are the side effects of Trimipramine?

Trimipramine may cause side effects such as increased heart rate, blurred vision, dryness in mouth, difficulty in urination, weight gain, constipation and orthostatic hypotension (sudden lowering of blood pressure on standing). Consult your doctor if any of these side effects do not go away or worry you.

Q. What if I miss a dose of Trimipramine?

If you have missed a dose of Trimipramine, take it as soon as you remember it. However, if it is almost time for your next dose, take it in the regular schedule and skip the missed dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Q. Can I just stop taking Trimipramine?

No, do not stop the medication abruptly even if you are feeling good as it may worsen your condition. Continue taking Trimipramine for the duration prescribed by your doctor to get maximum benefit. Consult your doctor If the side effects bother you or if you have completed your course of treatment. The doctor will suggest gradual dose reduction before taking you off this medicine completely.

Q. Can a pregnant woman take Trimipramine?

Do not take Trimipramine during pregnancy unless recommended by the doctor. It is given only if the benefits are clearly more than the risks involved. Studies have shown significant risks to the developing baby. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors and spasms. Hence, it is advised that you should consult your doctor if you are pregnant, planning to become pregnant or breastfeeding before taking this medicine.

Q. Does Trimipramine make you sleepy?

Yes, Trimipramine may make you feel sleepy. It is therefore advised that you do not drive, use any heavy machinery or do any work that requires concentration while taking Trimipramine. Also, avoid taking alcohol if you are being treated with Trimipramine as it will only increase your drowsiness.


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