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Trimipramine
INFORMATION ABOUT TRIMIPRAMINE
Trimipramine Uses
Trimipramine is used in the treatment of depression, Anxiety, bed-wetting, obsessive-compulsive disorder, insomnia and neuropathic pain.
How Trimipramine works
Trimipramine is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Common side effects of Trimipramine
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Increased heart rate, Weight gain, Dryness in mouth, Constipation, Difficulty in urination, Orthostatic hypotension (sudden lowering of blood pressure on standing)
CONTENT DETAILS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
03 Dec 2024 | 05:02 AM (UTC)
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Expert advice for Trimipramine
  • It may take 4 to 6 weeks for Trimipramine to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Trimipramine as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
  • It can take 2 to 3 weeks for Trimipramine to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Trimipramine, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Trimipramine, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Trimipramine is very less.
  • It may be extremely dangerous in overdose. 
Frequently asked questions for Trimipramine
Trimipramine belongs to a group of medicines known as antidepressants, used to treat depression. It works by restoring the chemical imbalance in the brain which helps to improve mood and behavior.
Before taking Trimipramine, you should tell your doctor if you are allergic to Trimipramine or any of its ingredients to avoid any allergic reactions. Inform your doctor if you have any problems with your heart, liver, thyroid, prostate or kidneys. Tell your doctor if you have or ever had epilepsy (seizures or fits), diabetes, or glaucoma. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Also, inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.
Yes, Trimipramine is effective if taken in the dose and duration prescribed by the doctor. Avoid skipping doses and tell your doctor if you experience any side effects while taking Trimipramine. The doctor may suggest ways to manage or prevent them. It may take a few weeks for you to see improvement in your symptoms. However, the treatment may be continued for a few months for effective management of your condition.
Trimipramine may cause side effects such as increased heart rate, blurred vision, dryness in mouth, difficulty in urination, weight gain, constipation and orthostatic hypotension (sudden lowering of blood pressure on standing). Consult your doctor if any of these side effects do not go away or worry you.
If you have missed a dose of Trimipramine, take it as soon as you remember it. However, if it is almost time for your next dose, take it in the regular schedule and skip the missed dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
No, do not stop the medication abruptly even if you are feeling good as it may worsen your condition. Continue taking Trimipramine for the duration prescribed by your doctor to get maximum benefit. Consult your doctor If the side effects bother you or if you have completed your course of treatment. The doctor will suggest gradual dose reduction before taking you off this medicine completely.
Do not take Trimipramine during pregnancy unless recommended by the doctor. It is given only if the benefits are clearly more than the risks involved. Studies have shown significant risks to the developing baby. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors and spasms. Hence, it is advised that you should consult your doctor if you are pregnant, planning to become pregnant or breastfeeding before taking this medicine.
Yes, Trimipramine may make you feel sleepy. It is therefore advised that you do not drive, use any heavy machinery or do any work that requires concentration while taking Trimipramine. Also, avoid taking alcohol if you are being treated with Trimipramine as it will only increase your drowsiness.