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    Information about Trimetazidine

    Trimetazidine uses

    Trimetazidine is used to prevent Angina (heart-related chest pain).

    How trimetazidine works

    Trimetazidine is an anti-anginal medication. It decreases the oxygen requirement of the heart by shifting its metabolism from fats to glucose. As a result, the heart works more efficiently.

    Common side effects of trimetazidine

    Headache, Vomiting, Dizziness, Weakness, Constipation, Nausea
    Content Details
    Written By
    Dr. Betina Chandolia
    MDS, BDS
    Reviewed By
    Dr. Shilpa Garcha
    MD (Pharmacology), MBBS
    Last updated on:
    20 Sep 2019 | 11:56 AM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Expert advice for Trimetazidine

    • Trimetazidine prevents new attacks of angina but does not stop an acute attack.
    • Does not affect heart rate, blood pressure at rest or during exercise.
    • Improves HbA1c and blood sugar levels in diabetes patients.
    • Avoid driving or using machinery if you feel dizzy after taking Trimetazidine.

    Frequently asked questions for Trimetazidine


    Q. Is Trimetazidine a beta blocker?

    No, Trimetazidine is not a beta blocker. It is an anti-anginal medicine which is used in combination with other medicines to treat angina pectoris (chest pain caused by coronary disease). It protects the heart cells from getting affected by the reduced oxygen supply during an episode of angina.

    Q. Who should not take Trimetazidine?

    You should not take Trimetazidine if you are allergic to it or have severe kidney problems. Patients with Parkinson’s disease should also avoid taking Trimetazidine. Parkinson’s disease is a disease of the brain which affects movement and causes trembling, rigid posture, slow movements and a shuffling, unbalanced walk.

    Q. Can Trimetazidine be used in elderly patients?

    Trimetazidine should be used with caution in patients aged more than 75 years of age. Usually, a lower dose is prescribed in elderly patients to reduce the chances of adverse effects. It is important to continuously monitor such patients.

    Q. Does taking Trimetazidine increases the risk of falling down frequently?

    Though it is rare, falls may occur with use of Trimetazidine. This may be due to instability while walking or fall in blood pressure while standing up. The risk may be higher in elderly patients. Therefore, they need to be more careful and should be monitored.

    Q. How should Trimetazidine be taken?

    You should take Trimetazidine exactly as prescribed by your doctor. It is meant for oral use. So, take the tablets with sufficient amount of liquid, e.g. a glass of water. You can take this medicine with or without food.

    Q. Does Trimetazidine cause drowsiness?

    Yes, Trimetazidine may make you feel dizzy and drowsy. Therefore, you should avoid driving or using heavy machinery in case it causes these side effects.

    Q. What are the possible side effects of Trimetazidine?

    The common side effects of Trimetazidine include dizziness, headache, abdominal pain, diarrhea, indigestion, and hives, rash and itching. Its use may also make you feel sick and weak. The rare side effects may include fast or irregular heartbeats (also called palpitations), fall in blood pressure on standing which can further cause dizziness, lightheadedness or fainting, fall, and flushing.

    Content on this page was last updated on 20 September, 2019, by Dr. Varun Gupta (MD Pharmacology)