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Trimebutine is used to help regulate movement of the intestinal tract and to treat symptoms of irritable bowel syndrome (spastic colon). It may also be used after an intestinal surgery.

How it works

Trimebutine belongs to a group of medicines known as spasmolytics. It works by slowing down or normalizing the abnormal movements of the bowel.

Common side effects

Nausea, Rash, Abdominal pain, Drowsiness, Anxiety, Breast enlargement, Breast pain, Constipation, Diarrhoea, Dizziness, Dry mouth, Altered taste, Difficulty in urination, Fatigue, Headache, Hearing disorder, Hot sensation, Cold sensation, Indigestion


Expert advice

  • Do not drive or use machinery while using trimebutine as it may cause dizziness.
  • Do not take alcohol as it may worsen the side effects of trimebutine.
  • Avoid concomitant use of trimebutine with other medicine such as tubocurarine.
  • Trimebutine is not recommended in children or adolescents under 12 years of age.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions


Q. Does trimebutine work?
Trimebutine works if taken as recommended for dosage and duration.
Q. How long does trimebutine take to work?
Trimebutine may take a few days to week to work; There are reports that its effects are observed in around 3 days to 2 weeks.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)