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For remission induction and remission consolidation treatment of acute nonlymphocytic leukemias.

How it works

Thioguanine nucleotides are incorporated into both the DNA and the RNA by phosphodiester linkages and inhibits tumor by inhibition of de novo purine synthesis; inhibition of purine nucleotide incorporation into the DNA and RNa blockade the utilization and synthesis of the purine nucleotides.

Common side effects

Nausea, Rash, Anemia, Dermatitis, Diarrhoea, Increased uric acid level in blood, Jaundice, Stomatitis, Loss of appetite, Reduced blood platelets, Vomiting


Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)